Monoclonal Antibody to Cyclin D1 (CCND1)

CCN-D1; BCL1; PRAD1; U21B31; G1/S-Specific Cyclin-D1; Parathyroid Adenomatosis 1; B-Cell CLL/Lymphoma 1; G1/S-Specific Cyclin D1; PRAD1 oncogene

SPECIFITY

The antibody is a mouse monoclonal antibody raised against CCND1. It has been selected for its ability to recognize CCND1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Biochemical Pharmacology Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells ScienceDirect: S0006295211002097
Leukemia & Lymphoma The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-62 human leukemia cells Pubmed: 24138332
The Journal of Clinical Endocrinology and Metabolism Antiproliferative and proapoptotic activity of sunitinib on endothelial and anaplastic thyroid cancer cells via inhibition of Akt and ERK1/2 phosphorylation and by down-regulation of cyclin-D1. Pubmed: 23969186
Nutrition and Cancer Common Food Additive Carrageenan Stimulates Wnt/ β-Catenin Signaling in Colonic Epithelium by Inhibition of Nucleoredoxin Reduction Pubmed:24328990
The International Journal of Biochemistry & Cell Biology MicroRNA-149 is epigenetically silenced tumor-suppressive microRNA, involved in cell proliferation and downregulation of AKT1 and cyclin D1 in human … pubmed:27783537
Scientific Reports Is there an association between enhanced choline and β-catenin pathway in breast cancer? A pilot study by MR Spectroscopy and ELISA. pubmed:28533512
Investigational new drugs Development of a dietary formulation of the SHetA2 chemoprevention drug for mice. pubmed:29273857
Biochemical Pharmacology Metronomic vinorelbine is directly active on Non Small Cell Lung Cancer cells and sensitizes the EGFRL858R/T790M cells to reversible EGFR tyrosine kinase … Pubmed:29660315
Apoptosis Licarin A induces cell death by activation of autophagy and apoptosis in non-small cell lung cancer cells Pubmed:29468481
Oncology Reports Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo Pubmed:29517106
Oncology Reports Lenvatinib exhibits antineoplastic activity in anaplastic thyroid cancer in vitro and in vivo Pubmed:29517103
Scientific Reports Is there an association between enhanced choline and β-catenin pathway in breast cancer? A pilot study by MR Spectroscopy and ELISA Pubmed: 28533512
Middle East Journal of Rehabilitation and Health Antiapoptotic Effects of Continuous Training and Selenium Consumption on the Liver Tissue of Cadmium-Exposed Rats Pubmed: 10.5812/mejrh.91278
European journal of medicinal chemistry Synthesis of novel S-linked dihydroartemisinin derivatives and evaluation of their anticancer activity Pubmed: 31216504
Catalog No. Related products for research use of Chicken (Gallus) Organism species Applications (RESEARCH USE ONLY!)
RPA585Ga01 Recombinant Cyclin D1 (CCND1) Positive Control; Immunogen; SDS-PAGE; WB.
PAA585Ga01 Polyclonal Antibody to Cyclin D1 (CCND1) WB; IHC; ICC; IP.
LAA585Ga71 Biotin-Linked Polyclonal Antibody to Cyclin D1 (CCND1) WB; IHC; ICC.
LAA585Ga81 FITC-Linked Polyclonal Antibody to Cyclin D1 (CCND1) WB; IHC; ICC; IF.
MAA585Ga21 Monoclonal Antibody to Cyclin D1 (CCND1) WB; IHC; ICC; IP.