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Eukaryotic Nesfatin 1 (NES1)

  • Product No.EPA242Ra61
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceEukaryotic expression
  • Host293F cell
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Nucleus, Secreted, Golgi apparatus
  • Predicted Molecular Mass48.6kDa
  • Accurate Molecular Mass49kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal25~Thr420 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point4.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 298  US$ 745  US$ 1490  US$ 4470  US$ 11175 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Bulletin of Clinical Psychopharmacology Plasma Nesfatin-1 Level May Be Associated with Disease Severity in Patients with Panic Disorder Psikofarmakoloji: 2043
Progress in Neuro-Psychopharmacology & Biological Psychiatry High plasma nesfatin-1 level in patients with major depressive disorder PubMed: 21163317
Endocrine Cord blood nesfatin-1 and apelin-36 levels in gestational diabetes mellitus SpringerLink: h978088657555w16
Bulletin of Clinical Psychopharmacology Increased Plasma Nesfatin-1 Levels in Patients with Obsessive Compulsive Disorder Psikofarmakoloji: 2212
Psychoneuroendocrinology. Decreased plasma nesfatin-1 levels in patients with generalized anxiety disorder PubMed: 22595767
Iranian Journal of Health and Physical activity Effects of Aerobic Training, with or without Zizyphus Jujuba Water Extraction, on Fundus Nesfatin-1, ATP, HDL-C, and LDL-C Concentrations in Female Rats Ijvst: Source
European Journal of Obstetrics & Gynecology and Reproductive Biology Decreased serum nesfatin-1 levels in endometriosis Pubmed: 24702902
Bulletin of Clinical Psychopharmacology Increased Plasma Nesfatin-1 Levels in Patients with Obsessive Compulsie Disorder. Psikofarmakoloji: Source
Current Pharmaceutical Design Role of NUCB2/nesfatin-1 as a possible biomarker. Pubmed: 23537082
Regulatory, Integrative and Comparative Physiology A role of nesfatin-1/NucB2 in dehydration-induced anorexia Pubmed:24829503
J Endocrinol Invest. Plasma nesfatin-1 levels are increased in patients with polycystic ovary syndrome Pubmed:24920281
Int J Surg. The potential role of BMI, plasma leptin, nesfatin-1 and ghrelin levels in the early detection of pancreatic necrosis and severe acute pancreatitis: a prospective cohort study. Pubmed:25448651
Hormone molecular biology and clinical investigation The effects of short-term high-intensity interval training vs. moderate-intensity continuous training on plasma levels of nesfatin-1 and inflammatory markers Pubmed:25581765
Turk J Gastroenterol. New hormones to predict the severity of gallstone-induced acute pancreatitis Pubmed:25599787
Respiration Is There a Relationship between Obstructive Sleep Apnea Syndrome Severity and Nesfatin-1? PubMed: 26088934
J Clin Res Pediatr Endocninol Correlation of Brain Neuropeptide (Nesfatin-1 and Orexin-A) Concentrations with Anthropometric and Biochemical Parameters in Malnourished Children PubMed: 26831553
Bosn J Basic Med Sci Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome PubMed: 26295295
Original Article / Orijinal Makale Relationship and Interaction between Anaerobic Sports Branches and Serum Nesfatin-1 Sayilar: 294
Gynecol Endocrinol Nesfatin-1 levels and metabolic markers in polycystic ovary syndrome PubMed: 26062107
International Journal of Neuroscience Serum nesfatin-1 levels: a potential new biomarker in patients with subarachnoid hemorrhage* Pubmed:26872406
未找到 Comparing the nesfatin-1 levels between individuals with subjective cognitive decline and mild cognitive impairment P.1.e.012.pdf
International Journal of Developmental Serum nesfatin-1 levels: a potential new biomarker in patients with subarachnoid hemorrhage. pubmed:26872406
Current Pharmaceutical Design Metabolic and Cardiovascular Actions of Nesfatin-1: Implications in Health and Disease pubmed:28137218
Arch Endocrinol Metab Serum nesfatin-1 levels are decreased in pregnant women newly diagnosed with gestational diabetes pubmed:28977160
Indian Journal of Psychiatry Serum NUCB2/nesfatin-1 levels in different stages of alcohol dependence: Is there a relationship with craving? pubmed:28529367
Biomedicine & Pharmacotherapy Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ Pubmed:29604590
Biochimica et Biophysica Acta Nesfatin-1 functions as a switch for phenotype transformation and proliferation of VSMCs in hypertensive vascular remodeling Pubmed:29627363
BMC Psychiatry Plasma nesfatin-1 level is associated with severity of depression in Chinese depressive patients Pubmed:29615007
Probiotics and Antimicrobial Proteins Mitra Zarrati, Mahsa Raji Lahiji, Eisa Salehi, Bahareh Yazdani, Elham Razmpoosh, Raheleh Shokouhi Shoormasti & Farzad Shidfar Pubmed: 30232744
An elevated serum level of nesfatin-1 may predict poor outcomes in patients with aneurysmal subarachnoid hemorrhages
clinical neurology and neurosurgery Relationshıp of spontaneous subarachnoid haemorrhage and cerebral aneurysm to serum Visfatin and Nesfatin-1 levels Pubmed: 32311618
Ann Nutr Metab Copeptin and Nesfatin-1 Are Interrelated Biomarkers with Roles in the Pathogenesis of Insulin Resistance in Chinese Children with Obesity Pubmed: 33027789
Endokrynologia Polska Assessing the blood concentration of new adipocytokines in patients with ischaemic stroke 33283259
Increased serum nesfatin-1 levels among adolescents diagnosed with major depressive disorder
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
EPA242Ra61 Eukaryotic Nesfatin 1 (NES1) Positive Control; Immunogen; SDS-PAGE; WB.
APA242Ra01 Active Nesfatin 1 (NES1) Cell culture; Activity Assays.
RPA242Ra01 Recombinant Nesfatin 1 (NES1) Positive Control; Immunogen; SDS-PAGE; WB.
APA242Ra61 Active Nesfatin 1 (NES1) Cell culture; Activity Assays.
PAA242Ra01 Polyclonal Antibody to Nesfatin 1 (NES1) WB; IHC; ICC; IP.
LAA242Ra81 FITC-Linked Polyclonal Antibody to Nesfatin 1 (NES1) WB; IHC; ICC; IF.
LAA242Ra71 Biotin-Linked Polyclonal Antibody to Nesfatin 1 (NES1) WB; IHC; ICC.
SEA242Ra ELISA Kit for Nesfatin 1 (NES1) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA242Ra ELISA Kit for Nesfatin 1 (NES1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA242Ra Multiplex Assay Kit for Nesfatin 1 (NES1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.