≡

Mouse Model for Uremia

Uraemia; Uremic poison; Uremic syndrome

  • Product No.DSI782Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by 5/6 nephrectomy
  • Model Animal StrainsC56BL/6 mice (SPF class), Male, 6~8W, 22~25g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period12 weeks
  • Modeling Method1. 3% pentobarbital sodium solution (80mg/kg) intraperitoneal injection of mice;
    2. The left kidney was exposed to the left side of the abdominal incision, and the upper and lower poles of the left kidney (about 1/3 of the renal volume) were ligated respectively. Cut down the upper and lower pole at the same time, gelatin sponge compression hemostasis 2 mins, and layer by layer suture of peritoneum and skin;
    3. 1 weeks later, the same method was applied to exposed the right kidney, the right kidney was removed after ligation of the right renal artery and ureter.
  • ApplicationsDisease Model
  • Downloadn/a
  • UOM Each case
  • FOB US$ 280 
    For more details, please contact local distributors!

Model Evaluation

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

GIVEAWAYS

INCREMENT SERVICES

Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
DSI782Mu01 Mouse Model for Uremia Disease Model