5-Hydroxytryptamine Transporter Linked Polymorphic Region (5-HTTLPR)

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Serotonin-Transporter-Linked Polymorphic Region; SERTLPR

5-Hydroxytryptamine Transporter Linked Polymorphic Region (5-HTTLPR)

5-HTTLPR (serotonin-transporter-linked polymorphic region) is a degenerate repeat polymorphic region in SLC6A4, the gene that codes for the serotonin transporter. The serotonin transporter (5-HTT) gene is a promising candidate for introducing the heritability of interindividual variation in personality and the genetic susceptibility for various psychiatric diseases. Transcription of the gene is modulated by a common polymorphism in its upstream regulatory region (5-HTT gene-linked polymorphic region: 5-HTTLPR). The 5-HTTLPR consists of variation of the repetitive sequence containing GC-rich, 20-23-bp-long repeat elements. A deletion/insertion in the 5-HTTLPR was first reported to create a short (S) allele and a long (L) allele (14- and 16-repeats, respectively).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of 5-Hydroxytryptamine Transporter Linked Polymorphic Region (5-HTTLPR) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to 5-Hydroxytryptamine Transporter Linked Polymorphic Region (5-HTTLPR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to 5-Hydroxytryptamine Transporter Linked Polymorphic Region (5-HTTLPR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for 5-Hydroxytryptamine Transporter Linked Polymorphic Region (5-HTTLPR) CLIA Kit Customized Service Offer
n/a ELISA Kit for 5-Hydroxytryptamine Transporter Linked Polymorphic Region (5-HTTLPR) ELISA Kit Customized Service Offer