Galectin Related Protein (GRP)

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LGALSL; Lectin, Galactoside-Binding-Like Protein

Galectin Related Protein (GRP)
Galectins are a family of animal lectins which share similar carbohydrate-recognition domains (CRDs) and an affinity for beta-galactosides. A novel human galectin-related protein named GRP (galectin-related protein; previously known as HSPC159) comprises only one conserved CRD with 38 additional N-terminal residues. The C-terminal fragment of human GRP (GRP-C; residues 38-172) containing the CRD has been expressed and purified. The protein was crystallized using the hanging-drop vapour-diffusion method from a solution containing 2% PEG 400 and 2M ammonium sulfate in 100 mM Tris-HCl buffer pH 7.5. Diffraction data were collected to a resolution limit of 2.0 angstroms at beamline 3W1A of Beijing Synchrotron Radiation Facility at 100 K. The estimated Matthews coefficient was 2.6 angstroms3 Da(-1), corresponding to 51.8% solvent content.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Galectin Related Protein (GRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Galectin Related Protein (GRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Galectin Related Protein (GRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Galectin Related Protein (GRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Galectin Related Protein (GRP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Galectin Related Protein (GRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Galectin Related Protein (GRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Galectin Related Protein (GRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Galectin Related Protein (GRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Galectin Related Protein (GRP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Galectin Related Protein (GRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Galectin Related Protein (GRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Galectin Related Protein (GRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Galectin Related Protein (GRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Galectin Related Protein (GRP) ELISA Kit Customized Service Offer
  1. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Expression, purification, crystallization and preliminary X-ray characterization of the GRP carbohydrate-recognition domain from Homo sapiens."Acta Crystallogr. F 62:474-476(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "Crystal structure of the C-terminal conserved domain of human GRP, a galectin-related protein, reveals a function mode different from those of galectins."Proteins 71:1582-1588(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Crystal structure of the putative carbohydrate recognition domain of human galectin-related protein."Proteins 72:804-808(2008) [PubMed] [Europe PMC] [Abstract]