CLOCK Interacting Pacemaker (CIPC)

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CLOCK-interacting protein, circadian

CLOCK Interacting Pacemaker (CIPC)
At the core of the mammalian circadian clock is a feedback loop in which the heterodimeric transcription factor CLOCK-Brain, Muscle Arnt-like-1 (BMAL1) drives expression of its negative regulators, periods (PERs) and cryptochromes (CRYs). CLOCK-Interacting Protein, Circadian (CIPC) is an additional negative-feedback regulator of the circadian clock. CIPC exhibits circadian regulation in multiple tissues, and it is a potent and specific inhibitor of CLOCK-BMAL1 activity that functions independently of CRYs. CIPC-CLOCK protein complexes are present in vivo, and depletion of endogenous CIPC shortens the circadian period length. CIPC is unrelated to known proteins and has no recognizable homologues outside vertebrates.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CLOCK Interacting Pacemaker (CIPC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CLOCK Interacting Pacemaker (CIPC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CLOCK Interacting Pacemaker (CIPC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CLOCK Interacting Pacemaker (CIPC) CLIA Kit Customized Service Offer
n/a ELISA Kit for CLOCK Interacting Pacemaker (CIPC) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CLOCK Interacting Pacemaker (CIPC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CLOCK Interacting Pacemaker (CIPC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CLOCK Interacting Pacemaker (CIPC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CLOCK Interacting Pacemaker (CIPC) CLIA Kit Customized Service Offer
n/a ELISA Kit for CLOCK Interacting Pacemaker (CIPC) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CLOCK Interacting Pacemaker (CIPC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CLOCK Interacting Pacemaker (CIPC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CLOCK Interacting Pacemaker (CIPC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CLOCK Interacting Pacemaker (CIPC) CLIA Kit Customized Service Offer
n/a ELISA Kit for CLOCK Interacting Pacemaker (CIPC) ELISA Kit Customized Service Offer