Testis Specific Protein, Y-Linked 8 (TSPY8)

[Edit]

Testis Specific Protein, Y-Linked 8 (TSPY8)
TSPY8 belongs to the nucleosome assembly protein (NAP) family.Nucleosome assembly proteins (NAPs) bind core histones, facilitate chromatin remodeling, and can act as transcriptional coactivators.
Its zygotic expression is restricted to neural cells, the outer cells of the ventral blood island (VBIs), and the ectoderm overlying the blood precursors.depletion of zygotic xNAP1L in embryos produces no obvious morphologic phenotype, but ablates -globin mRNA expression in the VBIs. Transcript levels of the hematopoietic precursor genes SCL and Xaml (Runx-1) are also reduced in the VBIs. Nucleosome assembly protein (NAP) family members are found in all eukaryotes, although primary sequence varies considerably among them, they share the ability to assemble nucleosomes in vitro.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Testis Specific Protein, Y-Linked 8 (TSPY8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Testis Specific Protein, Y-Linked 8 (TSPY8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Testis Specific Protein, Y-Linked 8 (TSPY8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Testis Specific Protein, Y-Linked 8 (TSPY8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Testis Specific Protein, Y-Linked 8 (TSPY8) ELISA Kit Customized Service Offer
  1. "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes." Nature 423:825-837(2003) [PubMed] [Europe PMC] [Abstract]