Male Specific Lethal 3 Like Protein 2 (MSL3L2)

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MSL3P1; Putative male-specific lethal-3 protein-like 2

Male Specific Lethal 3 Like Protein 2 (MSL3L2)
MSL3L2 Contains 1 chromo domain.May be involved in chromatin remodeling and transcriptional regulation. MSL3 encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. The deduced 521-amino acid MSL3L1 protein shares 30% overall sequence identity with Drosophila MSL3 and 86% identity with mouse Msl3l1, which the authors also identified.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Male Specific Lethal 3 Like Protein 2 (MSL3L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Male Specific Lethal 3 Like Protein 2 (MSL3L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Male Specific Lethal 3 Like Protein 2 (MSL3L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Male Specific Lethal 3 Like Protein 2 (MSL3L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Male Specific Lethal 3 Like Protein 2 (MSL3L2) ELISA Kit Customized Service Offer
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]