Synapse Differentiation Inducing Protein 1 (SYNDIG1)

[Edit]

C20orf39; DSPC2; TMEM90B; IFITMD5; SynDIG1 Interferon Induced Transmembrane Protein Domain Containing 5; Transmembrane protein 90B; Dispanin subfamily C member 2

Synapse Differentiation Inducing Protein 1 (SYNDIG1)
SYNDIG1 belongs to the capucin family. May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation. a type II transmembrane protein (SynDIG1) that regulates AMPA receptor content at developing synapses in dissociated rat hippocampal neurons. SynDIG1 colocalizes with AMPA receptors at synapses and at extrasynaptic sites and associates with AMPA receptors in heterologous cells and brain. Altered levels of SynDIG1 in cultured neurons result in striking changes in excitatory synapse number and function. SynDIG1-mediated synapse development is dependent on association with AMPA receptors via its extracellular C terminus. Intriguingly, SynDIG1 content in dendritic spines is regulated by neuronal activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synapse Differentiation Inducing Protein 1 (SYNDIG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synapse Differentiation Inducing Protein 1 (SYNDIG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synapse Differentiation Inducing Protein 1 (SYNDIG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synapse Differentiation Inducing Protein 1 (SYNDIG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synapse Differentiation Inducing Protein 1 (SYNDIG1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synapse Differentiation Inducing Protein 1 (SYNDIG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synapse Differentiation Inducing Protein 1 (SYNDIG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synapse Differentiation Inducing Protein 1 (SYNDIG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synapse Differentiation Inducing Protein 1 (SYNDIG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synapse Differentiation Inducing Protein 1 (SYNDIG1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synapse Differentiation Inducing Protein 1 (SYNDIG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synapse Differentiation Inducing Protein 1 (SYNDIG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synapse Differentiation Inducing Protein 1 (SYNDIG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synapse Differentiation Inducing Protein 1 (SYNDIG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synapse Differentiation Inducing Protein 1 (SYNDIG1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The dispanins: a novel gene family of ancient origin that contains 14 human members."PLoS ONE 7:E31961-E31961(2012) [PubMed] [Europe PMC] [Abstract]