Translocated Actin Recruiting Phosphoprotein (TARP)

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Translocated Actin Recruiting Phosphoprotein (TARP)
The translocated actin-recruiting phosphoprotein (Tarp) is a protein that may mediate the invasion of epithelial cells by Chlamydia trachomatis using a type three secretion system. Belongs to the chlamydial CPn_0572/CT_456/TC_0741 family. Appears to initiate or participate in signaling events that regulate the actin recruitment, which ultimately leads to internalization. Secreted via type III secretion system and translocated into host cell
Phosphorylated on a tyrosine on attachment to the host cell. Tyrosine phosphorylation is temporally and spatially associated with recruitment of actin to the site of chlamydial entry. Phosphorylated Tarp seems to remain cytoplasmically exposed on the inclusion membrane at one side of internalized elementary bodies for several hours after entry

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Translocated Actin Recruiting Phosphoprotein (TARP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Translocated Actin Recruiting Phosphoprotein (TARP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocated Actin Recruiting Phosphoprotein (TARP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocated Actin Recruiting Phosphoprotein (TARP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Translocated Actin Recruiting Phosphoprotein (TARP) ELISA Kit Customized Service Offer
  1. "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis."Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract]