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Triggering Receptor Expressed On Myeloid Cells 3 (TREM3)

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Triggering Receptor Expressed On Myeloid Cells 3 (TREM3)
CCC S493
MGI 1930003
PubMed 20337897
RGD 1305477
UniProt Q9JKE1
TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17. TREM-3 transcripts could also be detected at low levels in T cell lines, but were not detectable in NK, B cell, or mast cell lines. Furthermore, in macrophage cells, transcripts for TREM-3 were up-regulated by LPS, but were down-regulated by IFN-gamma. Like TREM-1 and TREM-2, TREM-3 signals through DAP12, and when TREM-3 is transfected into an NK cell line it mediates redirected lysis. Thus, TREM-3 functions as an activating receptor. Analysis of the mouse genome reveals that the gene for TREM-3 lies adjacent to the gene for TREM-1 and in close proximity to a number of other single Ig domain receptors, including TREM-2.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Triggering Receptor Expressed On Myeloid Cells 3 (TREM3) ELISA Kit Customized Service Offer
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