Retinol Dehydrogenase 1 (RDH1)
Mouse rdh1 encodes retinol dehydrogenase type 1 (RDH1), a short-chain dehydrogenase, which recognizes as substrates all-trans-retinol, 9-cis-retinol, 5α-androstan-3,17-diol and 5α-androstan-3-ol-17-one. RDH1 is the most efficient known mouse short-chain dehydrogenase that catalyzes dehydrogenation of all-trans-retinol, and contributes to a reconstituted path of all-trans-retinoic acid biosynthesis, when coexpressed in reporter cells with any one of three retinal dehydrogenases. Rdh1 shows widespread, if not ubiquitous, mRNA expression in the mouse beginning no later than embryo day 7. Rdh1 consists of four exons and three introns and spans not, vert, similar14412 bp. Rdh1 is a single copy gene that maps to chromosome 10D3 with rdh5–9, but no known disorder maps precisely to rdh1. Rdh1 has three transcription start sites in kidney and one start site in liver.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinol Dehydrogenase 1 (RDH1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinol Dehydrogenase 1 (RDH1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinol Dehydrogenase 1 (RDH1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinol Dehydrogenase 1 (RDH1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinol Dehydrogenase 1 (RDH1) ELISA Kit Customized Service Offer
  1. "Molecular characterization of a mouse short chain dehydrogenase/reductase active with all-trans-retinol in intact cells, mRDH1."J. Biol. Chem. 276:44083-44090(2001) [PubMed] [Europe PMC] [Abstract]