Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1)

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HsMAD1; MAD1; PIG9; TP53I9; TXBP181; Mitotic spindle assembly checkpoint protein MAD1; Mitotic checkpoint MAD1 protein homolog; Tax-binding protein 181

Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1)
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
MAD1L1 functions as a homodimer. It localizes to the centrosome during metaphase and to the spindle midzone and the midbody during anaphase and telophase. Expression of either Tax or a transdominant-negative MAD1L1 results in multinucleated cells, a phenotype consistent with a loss of MAD1L1 function.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Monoclonal Antibody Customized Service Offer
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Assay Kits SEP874Hu ELISA Kit for Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Polyclonal Antibody Customized Service Offer
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n/a ELISA Kit for Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitotic Arrest Deficient 1 Like Protein 1 (MAD1L1) ELISA Kit Customized Service Offer
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