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Wingless Type MMTV Integration Site Family, Member 3A (WNT3A)

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Wingless Type MMTV Integration Site Family, Member 3A (WNT3A)
CCC P155
HGNC 15983
MGI 98956
PubMed 24254835
RGD 1308057
UniProt P56704
Wiki WNT3A
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT3A is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. WNT3A encodes a deduced 352-amino acid protein containing an N-linked glycosylation site and residues conserved among members of the WNT family. The WNT3A protein shares 84.9% sequence identity with human WNT3 .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP155Hu01 Recombinant Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAP155Hu01 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
MAP155Hu21 Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC
MAP155Hu22 Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
MAP155Hu23 Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
MAP155Hu24 Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
MAP155Hu25 Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
Assay Kits SCP155Mi CLIA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Chemiluminescent immunoassay for Antigen Detection.
SEP155Mi ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
HEP155Mi High Sensitive ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
SEP155Hu ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
HEP155Hu High Sensitive ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP155Mu01 Recombinant Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Positive Control; Immunogen; SDS-PAGE; WB.
RPP155Mu02 Recombinant Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAP155Mu01 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
PAP155Mu02 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
Assay Kits SCP155Mi CLIA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Chemiluminescent immunoassay for Antigen Detection.
SEP155Mi ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
HEP155Mi High Sensitive ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
SEP155Mu ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
HEP155Mu High Sensitive ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP155Ra01 Recombinant Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAP155Ra01 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
MAP155Ra21 Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
Assay Kits SCP155Mi CLIA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Chemiluminescent immunoassay for Antigen Detection.
SEP155Mi ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
HEP155Mi High Sensitive ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
SEP155Ra ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.
HEP155Ra High Sensitive ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP155Bo01 Recombinant Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAP155Bo01 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3A (WNT3A) ELISA Kit Customized Service Offer
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  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue."Cancer Res. 54:2615-2621(1994) [PubMed] [Europe PMC] [Abstract]
  6. "Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells."Cell 125:509-522(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6."J. Biol. Chem. 285:9172-9179(2010) [PubMed] [Europe PMC] [Abstract]
  8. "WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification."J. Cell Sci. 123:3357-3367(2010) [PubMed] [Europe PMC] [Abstract]
  9. "APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex."Nature 464:1043-1047(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling."Cell. Signal. 23:837-848(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Disulfide bond requirements for active wnt ligands."J. Biol. Chem. 289:18122-18136(2014) [PubMed] [Europe PMC] [Abstract]
  12. "Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupine."Nat. Chem. Biol. 10:61-68(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Notum deacylates Wnt proteins to suppress signalling activity."Nature 519:187-192(2015) [PubMed] [Europe PMC] [Abstract]