Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1)

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Fibrocystin-L

Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1)
The 13,801-bp transcript was amplified by RT-PCR as 16 fragments and sequenced. PKHD1L1 covers a genomic region of 168 kb and encodes a large protein (fibrocystin-L). Fibrocystin-L was predicted to be a large receptor protein (4,243 amino acids; 466 kD) with a signal peptide, single transmembrane domain, and short cytoplasmic tail.
Fibrocystin-L is homologous to fibrocystin throughout most of the extracellular region, with overall identity of 25.0% and similarity of 41.5%. Fibrocystin-L has extracellular domains similar to fibrocystin with 14 copies of the TIG domain and 2 regions of significant homology to the protein TMEM2. The Fugu fish has a fibrocystin-L ortholog but no fibrocystin, suggesting that the newly identified protein may be the ancestral form.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polycystic Kidney And Hepatic Disease 1 Like Protein 1 (PKHD1L1) ELISA Kit Customized Service Offer
  1. "PKHDL1, a homolog of the autosomal recessive polycystic kidney disease gene, encodes a receptor with inducible T lymphocyte expression."Hum. Mol. Genet. 12:685-698(2003) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]