Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1)

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Polycystin-1L1; PC1-like 1 protein

Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1)
PKD1L1 encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined. The deduced 2,849-amino acid protein contains 11 putative transmembrane segments, 2 Ig-like PKD domains, a small REJ domain, a GPS domain, an LH2/PLAT domain, and a coiled-coil domain, all of which are found in polycystin-1 (PKD1). Two shorter, alternatively spliced PKD1L1 transcripts, designated PDK1L1a and PKD1L1b, contain 7 and 6 putative transmembrane domains, respectively.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Polycystic Kidney Disease 1 Like Protein 1 (PKD1L1) ELISA Kit Customized Service Offer
  1. "The sequence, expression, and chromosomal localization of a novel polycystic kidney disease 1-like gene, PKD1L1, in human."Genomics 79:376-386(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Direct recording and molecular identification of the calcium channel of primary cilia."Nature 504:315-318(2013) [PubMed] [Europe PMC] [Abstract]
  4. "BMPER mutation in diaphanospondylodysostosis identified by ancestral autozygosity mapping and targeted high-throughput sequencing."Am. J. Hum. Genet. 87:532-537(2010) [PubMed] [Europe PMC] [Abstract]