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Casein Alpha (CSN1)

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CASa; CSN1; CSN1S1; Casein Alpha S1; Caseinate; Caseine/caséine/Kasein/caseína; Alpha-S1-casein; Casoxin-D

Casein Alpha (CSN1)
CCC J333
HGNC 2445
MGI 88540
PubMed 11854419
RGD 2430
UniProt P47710
Milk casein can be separated by urea starch electrophoresis into 3 regions, alpha, beta, and kappa casein. Alpha and beta variants are present in the human population. In Italy the frequency of the 2 alpha alleles was 0.908 and 0.092; 2 beta alleles had a frequency of 0.678 and 0.322. the human alpha-S1, beta-, and kappa-casein genes are closely linked and arranged in that order. By fluorescence in situ hybridization, they demonstrated that the casein gene family is localized to 4q21.1. the human 'locus' comprises at least 4 casein genes: 3 genes encoding calcium-sensitive, casein-like genes, and 1 kappa-casein gene, in the order alpha-s1--beta--alpha-s2--kappa. The approximate size of the human casein gene locus is 350 kb. the casein cluster is located within 700 kb of the albumin gene cluster, which is located on 4q13.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ333Hu01 Recombinant Casein Alpha (CSN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAJ333Hu21 Monoclonal Antibody to Casein Alpha (CSN1) WB; IHC; ICC; IP.
PAJ333Hu01 Polyclonal Antibody to Casein Alpha (CSN1) WB
Assay Kits SEJ333Hu ELISA Kit for Casein Alpha (CSN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ333Mu01 Recombinant Casein Alpha (CSN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ333Mu01 Polyclonal Antibody to Casein Alpha (CSN1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Casein Alpha (CSN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Casein Alpha (CSN1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ333Ra01 Recombinant Casein Alpha (CSN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Casein Alpha (CSN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Casein Alpha (CSN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Casein Alpha (CSN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Casein Alpha (CSN1) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ333Bo01 Recombinant Casein Alpha (CSN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAJ333Bo21 Monoclonal Antibody to Casein Alpha (CSN1) WB; IHC; ICC; IP.
PAJ333Bo01 Polyclonal Antibody to Casein Alpha (CSN1) WB; IHC; ICC; IP.
Assay Kits SEJ333Bo ELISA Kit for Casein Alpha (CSN1) Enzyme-linked immunosorbent assay for Antigen Detection.
HEJ333Bo High Sensitive ELISA Kit for Casein Alpha (CSN1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Characterization of three types of human alpha s1-casein mRNA transcripts."Biochem. J. 309:237-242(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The gene encoding alpha s1-casein is expressed in human mammary epithelial cells during lactation."Lait 76:525-537(1996)
  5. "Human alpha S1-casein like protein: purification and N-terminal sequence determination."Biol. Chem. Hoppe-Seyler 375:149-151(1994) [PubMed] [Europe PMC] [Abstract]
  6. "Human alpha s1-casein: purification and characterization."Comp. Biochem. Physiol. 111B:75-81(1995) [PubMed] [Europe PMC] [Abstract]
  7. "On studying protein phosphorylation patterns using bottom-up LC-MS/MS: the case of human alpha-casein."Analyst 132:768-776(2007) [PubMed] [Europe PMC] [Abstract]
  8. "Analysis of the human casein phosphoproteome by 2-D electrophoresis and MALDI-TOF/TOF MS reveals new phosphoforms."J. Proteome Res. 7:5017-5027(2008) [PubMed] [Europe PMC] [Abstract]
  9. "The phosphorylation pattern of human alphas1-casein is markedly different from the ruminant species."Eur. J. Biochem. 270:3651-3655(2003) [PubMed] [Europe PMC] [Abstract]
  10. "Genomic organization and chromosomal localization of the human casein gene family."Hum. Genet. 99:368-373(1997) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]