Rheumatoid Arthritis (RA)

Arthritis is a form of joint disorder that involves inflammation in one or more joints.There are over 100 different forms of arthritis.The most common form of arthritis is osteoarthritis, a result of trauma to the joint, infection of the joint, or age. Other arthritis forms are rheumatoid arthritis, psoriatic arthritis, and related autoimmune diseases. Septic arthritis is caused by joint infection. Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints.

Models for rheumatoid arthritis can be used to aid in understanding the mechanism of action of novel anti-inflammatory compounds. Adjuvant administration induced polyarticular and systemic inflammation, which included spleen and liver. In the liver, multifocal hepatic granulomas were observed. Studies indicate that arthritis model is accompanied by an initial increased release of excitatory amino acids (EAA's) at the time of injection which is dependent on the activation of both non-NMDA and NMDA receptors. 

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Models DSI522Mu01 Mouse Model for Rheumatoid Arthritis (RA) Used to study the pathogenesis of rheumatoid arthritis (RA) and to provide an ideal experimental model for drug efficacy.
DSI522Mu03 Mouse Model for Rheumatoid Arthritis (RA) n/a
Tissues n/a Tissue of Rheumatoid Arthritis (RA) (If Necessary) Tissue Customized Service Offer
Serums n/a Serums of Rheumatoid Arthritis (RA) (If Necessary) Serums Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Models DSI522Ra01 Rat Model for Rheumatoid Arthritis (RA) The model is used to study the pathogenesis of rheumatoid arthritis (RA) and to provide an ideal experimental model for drug efficacy.
DSI522Ra03 Rat Model for Rheumatoid Arthritis (RA) n/a
Tissues TSI522Ra65 Rat Synovium Tissue of Rheumatoid Arthritis (RA) Paraffin slides for pathologic research: IHC,IF and HE,Masson and other stainings
TSI522Ra67 Rat Ankle Tissue of Rheumatoid Arthritis (RA) Paraffin slides for pathologic research: IHC,IF and HE,Masson and other stainings
Serums n/a Serums of Rheumatoid Arthritis (RA) (If Necessary) Serums Customized Service Offer

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Models DSI522Gu02 Cavia Model for Rheumatoid Arthritis (RA) n/a
DSI522Gu01 Cavia Model for Rheumatoid Arthritis (RA) n/a
DSI522Gu03 Cavia Model for Rheumatoid Arthritis (RA) n/a
Tissues n/a Tissue of Rheumatoid Arthritis (RA) (If Necessary) Tissue Customized Service Offer
Serums n/a Serums of Rheumatoid Arthritis (RA) (If Necessary) Serums Customized Service Offer

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Models DSI522Rb02 Rabbit Model for Rheumatoid Arthritis (RA) n/a
DSI522Rb01 Rabbit Model for Rheumatoid Arthritis (RA) n/a
Tissues n/a Tissue of Rheumatoid Arthritis (RA) (If Necessary) Tissue Customized Service Offer
Serums n/a Serums of Rheumatoid Arthritis (RA) (If Necessary) Serums Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Models n/a Model for Rheumatoid Arthritis (RA) Disease Model Customized Service Offer
Tissues n/a Tissue of Rheumatoid Arthritis (RA) (If Necessary) Tissue Customized Service Offer
Serums n/a Serums of Rheumatoid Arthritis (RA) (If Necessary) Serums Customized Service Offer