Cerebellar Granule Cells (CGC)

Granule cells are found within the granular layer of the cerebellum, the dentate gyrus of the hippocampus, the superficial layer of the dorsal cochlear nucleus, the olfactory bulb, and the cerebral cortex.The cerebellar granule cells (CGC) are the most abundant type of cortical neurons in cerebellum. in humans, estimates of their total number average around 50 billion, which means that they constitute about 3/4 of the brain's neurons.CGCs undergoes an apoptotic type of naturally occurring neuronal death(NOND) shortly after their generation, but also that some underlying molecular mechanisms are different in CGC progenitors/precursors or fully differentiated CGCs.