Choroid Plexus Endothelial Cells (CPEC)

The choroid plexus is located in the ventricle of the brain, which is the main area of the cerebrospinal fluid. The choroid plexus is composed of a single layer of epithelial cells, which form the blood cerebrospinal fluid barrier around the blood vessel center. The choroid plexus capillaries contain a layer of vascular endothelial cells, which are blocked by the small holes, to form the septum between the lumen and the interstitial space.

Studies have shown that choroid plexus endothelial cells (CPEC) expressed high levels of GLUT1 glucose transporter, the high density of glucose transporter to ensure the choroidal epithelial and endothelial cells with certain metabolic capacity, to maintain the ionic gradients across the blood cerebrospinal fluid barrier and secretory function. choroid plexus endothelial cells play a role in brain development, maturation, aging, endocrine regulation and pathogenesis of neurodegenerative diseases.