Dermal Mast Cells (DMC)

A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell. Specifically, it is a type of granulocyte derived from the myeloid stem cell that is a part of the immune and neuroimmune systems and contains many granules rich in histamine and heparin. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing, angiogenesis, immune tolerance, defense against pathogens, and blood–brain barrier function.The mast cell is very similar in both appearance and function to the basophil, another type of white blood cell. Although mast cells were once thought to be tissue resident basophils, it has been shown that the two cells develop from different hematopoietic lineages and thus cannot be the same cells.

Dermal mast cells (DMC) migrate from the skin to the draining lymph nodes has a prominent role in activating systemic immune suppression. UV-induced keratinocyte-derived platelet-activating factor (PAF) activates mast cell migration, in part by upregulating the expression of CXCR4 on the surface of mast cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI033Hu01 Primary Human Dermal Mast Cells (DMC) Primary Cells
Extracts n/a Extract of Dermal Mast Cells (DMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums n/a Medium for Dermal Mast Cells (DMC) (If Necessary) Cell Culture Medium Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI033Mu01 Primary Mouse Dermal Mast Cells (DMC) Primary Cells
Extracts n/a Extract of Dermal Mast Cells (DMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums n/a Medium for Dermal Mast Cells (DMC) (If Necessary) Cell Culture Medium Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI033Ra01 Primary Rat Dermal Mast Cells (DMC) Primary Cells
Extracts n/a Extract of Dermal Mast Cells (DMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums n/a Medium for Dermal Mast Cells (DMC) (If Necessary) Cell Culture Medium Customized Service Offer

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI033Rb01 Primary Rabbit Dermal Mast Cells (DMC) Primary Cells
Extracts n/a Extract of Dermal Mast Cells (DMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums n/a Medium for Dermal Mast Cells (DMC) (If Necessary) Cell Culture Medium Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI033Ca01 Primary Canine Dermal Mast Cells (DMC) Primary Cells
Extracts n/a Extract of Dermal Mast Cells (DMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums n/a Medium for Dermal Mast Cells (DMC) (If Necessary) Cell Culture Medium Customized Service Offer