Retinoic Acid Receptor Responder 1 (RARRES1)

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TIG1; PEIG1; Tazarotene-Induced Gene-1; Phorbol ester-induced gene 1 protein; RAR-responsive protein TIG1

Retinoic Acid Receptor Responder 1 (RARRES1)
RARRES1 was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.Strong RARRES1 expression could be induced by RAR-specific but not RXR-specific agents. In situ hybridization analysis showed that treatment of psoriatic rafts or patient skin lesions with tazarotene induces RARRES1 expression. Nonlesional and sham-treated lesional psoriatic skin showed no expression of RARRES1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH255Hu01 Recombinant Retinoic Acid Receptor Responder 1 (RARRES1) Positive Control; Immunogen; SDS-PAGE; WB.
RPH255Hu02 Recombinant Retinoic Acid Receptor Responder 1 (RARRES1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAH255Hu21 Monoclonal Antibody to Retinoic Acid Receptor Responder 1 (RARRES1) WB; IHC; ICC; IP.
PAH255Hu01 Polyclonal Antibody to Retinoic Acid Receptor Responder 1 (RARRES1) WB; IHC; ICC; IP.
Assay Kits SEH255Hu ELISA Kit for Retinoic Acid Receptor Responder 1 (RARRES1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinoic Acid Receptor Responder 1 (RARRES1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinoic Acid Receptor Responder 1 (RARRES1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinoic Acid Receptor Responder 1 (RARRES1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinoic Acid Receptor Responder 1 (RARRES1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinoic Acid Receptor Responder 1 (RARRES1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinoic Acid Receptor Responder 1 (RARRES1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinoic Acid Receptor Responder 1 (RARRES1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinoic Acid Receptor Responder 1 (RARRES1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinoic Acid Receptor Responder 1 (RARRES1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinoic Acid Receptor Responder 1 (RARRES1) ELISA Kit Customized Service Offer
  1. "Tazarotene-induced gene 1 (TIG1), a novel retinoic acid receptor-responsive gene in skin."J. Invest. Dermatol. 106:269-274(1996) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Identification by differential display of a mRNA specifically induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells."Cell. Mol. Biol. 42:797-804(1996) [PubMed] [Europe PMC] [Abstract]
  4. "Tumor suppressor RARRES1 interacts with cytoplasmic carboxypeptidase AGBL2 to regulate the alpha-tubulin tyrosination cycle."Cancer Res. 71:1219-1228(2011) [PubMed] [Europe PMC] [Abstract]