S-Adenosyl Methionine (SAM)

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SAMe; SAM-e; S-Adenosylmethionine; S-(5'-Adenosyl)-L-Methionine Chloride

S-Adenosyl Methionine (SAM)
-Adenosyl methionine (SAM, ) is a common co-substrate involved in methyl group transfers. SAM-e was first discovered in Italy by G. L. Cantoni in 1952. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver.The methyl group (CH3) attached to the methionine sulfur atom in SAM is chemically reactive. This allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group from SAM to various substrates such as nucleic acids, proteins, and lipids.In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPG414Ge11 BSA Conjugated S-Adenosyl Methionine (SAM) Immunogen; SDS-PAGE; WB.
CPG414Ge21 OVA Conjugated S-Adenosyl Methionine (SAM) Immunogen; SDS-PAGE; WB.
Antibodies PAG414Ge01 Polyclonal Antibody to S-Adenosyl Methionine (SAM) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
PAG414Ge02 Polyclonal Antibody to S-Adenosyl Methionine (SAM) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
Assay Kits CEG414Ge ELISA Kit for S-Adenosyl Methionine (SAM) Enzyme-linked immunosorbent assay for Antigen Detection.