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Endoplasmic Reticulum Protein 44 (ERP44)

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TXNDC4; PDIA10; Thioredoxin Domain Containing 4; Protein Disulfide Isomerase Family A,Member 10

Endoplasmic Reticulum Protein 44 (ERP44)
CCC F404
HGNC 18311
MGI 1923549
PubMed 11847130
RGD 1309176
UniProt Q9BS26
Wiki ERP44
The transcript contains a repetitive element in the 3-prime UTR, and the deduced 451-amino acid protein has an apparent molecular mass of 50 kD, as estimated by SDS-PAGE. KIAA0573 shares weak homology with barley protein disulfide isomerase precursor. RT-PCR detected robust expression in all tissues examined.
ERp44, deduced 436-amino acid protein has an N-terminal endoplasmic reticulum (ER) targeting signal sequence. After cleavage, the calculated molecular mass of ERp44 is 43.9 kD. ERp44 also contains a thioredoxin-like domain, which includes a CRFS motif; a calsequestrin -like domain; and a C-terminal ER retention signal (RDEL). The CRFS motif is present in mouse, fly, and nematode ERp44 homologs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF404Hu01 Recombinant Endoplasmic Reticulum Protein 44 (ERP44) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Endoplasmic Reticulum Protein 44 (ERP44) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endoplasmic Reticulum Protein 44 (ERP44) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Endoplasmic Reticulum Protein 44 (ERP44) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endoplasmic Reticulum Protein 44 (ERP44) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF404Mu01 Recombinant Endoplasmic Reticulum Protein 44 (ERP44) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF404Mu01 Polyclonal Antibody to Endoplasmic Reticulum Protein 44 (ERP44) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Endoplasmic Reticulum Protein 44 (ERP44) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endoplasmic Reticulum Protein 44 (ERP44) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Endoplasmic Reticulum Protein 44 (ERP44) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Endoplasmic Reticulum Protein 44 (ERP44) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endoplasmic Reticulum Protein 44 (ERP44) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Endoplasmic Reticulum Protein 44 (ERP44) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endoplasmic Reticulum Protein 44 (ERP44) ELISA Kit Customized Service Offer
  1. "ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family."EMBO J. 21:835-844(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44."EMBO J. 22:5015-5022(2003) [PubMed] [Europe PMC] [Abstract]
  8. "Towards complete analysis of the platelet proteome."Proteomics 2:288-305(2002) [PubMed] [Europe PMC] [Abstract]
  9. "Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44."Cell 120:85-98(2005) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  12. "Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail."EMBO Rep. 9:642-647(2008) [PubMed] [Europe PMC] [Abstract]