Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1)

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GLUH1; GLUR1; GLURA; HBGR1; GluR-K1; AMPA-selective glutamate receptor 1

Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1)
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE801Hu01 Recombinant Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAE801Hu21 Monoclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) WB; IHC; ICC; IP.
PAE801Hu01 Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) WB; IHC; ICC; IP.
Assay Kits SEE801Hu ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE801Ra01 Recombinant Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE801Ra01 Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) WB; IHC; ICC; IP.
MAE801Ra21 Monoclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) WB; IHC; ICC; IP.
Assay Kits SEE801Ra ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Polyclonal Antibody Customized Service Offer
Assay Kits SEE801Rb ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Enzyme-linked immunosorbent assay for Antigen Detection.
HEE801Rb High Sensitive ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Molecular cloning and chromosomal localization of one of the human glutamate receptor genes."Proc. Natl. Acad. Sci. U.S.A. 88:7557-7561(1991) [PubMed] [Europe PMC] [Abstract]
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  3. "Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors."Proc. Natl. Acad. Sci. U.S.A. 89:1443-1447(1992) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins."Neuron 68:1082-1096(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating."Proc. Natl. Acad. Sci. U.S.A. 107:16315-16319(2010) [PubMed] [Europe PMC] [Abstract]
  9. "A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors."J. Neurosci. 33:9840-9845(2013) [PubMed] [Europe PMC] [Abstract]