Apoptosis Inhibitor 5 (API5)

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MIG8; FIF; AAC11; API5L1; XAGL; Cell migration-inducing gene 8; Antiapoptosis clone 11; Fibroblast Growth Factor 2-Interacting Factor 2; Migration-Inducing Protein MIG8

Apoptosis Inhibitor 5 (API5)
AAC11 was cloned by database analysis and screening gingiva and leukemia cDNA libraries. The deduced 504-amino acid human protein shares a high degree of identity with the long mouse protein. AAC11 contains several protein phosphorylation sites, 2 N-glycosylation sites, and a leucine-rich sequence with weak similarity to a leucine zipper motif. Northern blot analysis detected a major Aac11 transcript in all adult and embryonic mouse tissues examined and several other transcripts expressed in a tissue-specific manner. AAC11 expression was also detected in several human tumor cell lines. Western blot analysis of mouse fibroblasts detected a major 55-kD protein and a minor 25-kD protein, corresponding to the long and short Aac11 isoforms, respectively.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE234Hu01 Recombinant Apoptosis Inhibitor 5 (API5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE234Hu01 Polyclonal Antibody to Apoptosis Inhibitor 5 (API5) WB; IHC; ICC; IP.
MAE234Hu21 Monoclonal Antibody to Apoptosis Inhibitor 5 (API5) WB; IHC; ICC; IP.
Assay Kits SEE234Hu ELISA Kit for Apoptosis Inhibitor 5 (API5) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Apoptosis Inhibitor 5 (API5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Apoptosis Inhibitor 5 (API5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Apoptosis Inhibitor 5 (API5) Polyclonal Antibody Customized Service Offer
Assay Kits SEE234Mu ELISA Kit for Apoptosis Inhibitor 5 (API5) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Apoptosis Inhibitor 5 (API5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Apoptosis Inhibitor 5 (API5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Apoptosis Inhibitor 5 (API5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Apoptosis Inhibitor 5 (API5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Apoptosis Inhibitor 5 (API5) ELISA Kit Customized Service Offer
  1. "AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal."Cancer Res. 57:4063-4069(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning and fine mapping of API5L1, a novel human gene strongly related to an antiapoptotic gene."Cytogenet. Cell Genet. 84:164-166(1999) [PubMed] [Europe PMC] [Abstract]
  3. "FIF [fibroblast growth factor-2 (FGF-2)-interacting-factor], a nuclear putatively antiapoptotic factor, interacts specifically with FGF-2."Mol. Endocrinol. 14:1709-1724(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]