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Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE)

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SNRP-E; B-raf; SME; Sm-E

Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE)
CCC D917
HGNC 11161
MGI 98346
PubMed 23246290
RGD 1592561
UniProt P62304
Wiki SNRPE
SNRPE is 1 of 4 'core' proteins associated with all known snRNAs in the U family.The gene for the E protein is 9 kb long and contains 5 exons. The sequence is known for 9 closely related genes that have several features of processed pseudogenes. The longest open reading frame coded for a basic 92-amino acid protein which had an amino acid sequence in perfect agreement with that obtained from purified E protein.At least one of the SNRPE pseudogenes is linked to a signal transduction G protein gene that also maps to chromosome 1. Two other small nuclear ribonucleoprotein (snRNP) components--the U1 RNA 'true' multigene family and a group of class I U1 pseudogenes--are located on chromosome 1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD917Hu01 Recombinant Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE) ELISA Kit Customized Service Offer
  1. "The complete primary structure of the human snRNP E protein."Nucleic Acids Res. 16:10593-10605(1988) [PubMed] [Europe PMC] [Abstract]
  2. "The small nuclear ribonucleoprotein E protein gene contains four introns and has upstream similarities to genes for ribosomal proteins."J. Biol. Chem. 263:17772-17779(1988) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence of a human Sm autoimmune antigen. The multigene family contains a processed pseudogene."J. Biol. Chem. 262:9931-9934(1987) [PubMed] [Europe PMC] [Abstract]
  6. "Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein."EMBO J. 20:5470-5479(2001) [PubMed] [Europe PMC] [Abstract]
  7. "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis."RNA 8:426-439(2002) [PubMed] [Europe PMC] [Abstract]
  8. "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome."RNA 10:929-941(2004) [PubMed] [Europe PMC] [Abstract]
  9. "An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs."Cell 135:497-509(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Mutations in SNRPE, which encodes a core protein of the spliceosome, cause autosomal-dominant hypotrichosis simplex."Am. J. Hum. Genet. 92:81-87(2013) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution."Nature 458:475-480(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis."Nature 473:536-539(2011) [PubMed] [Europe PMC] [Abstract]
  15. "Structural basis of assembly chaperone-mediated snRNP formation."Mol. Cell 49:692-703(2013) [PubMed] [Europe PMC] [Abstract]