Vanin 3 (VNN3)

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Vascular non-inflammatory molecule 3

Vanin 3 (VNN3)
By EST database analysis, Granjeaud et al. (1999) identified a novel human VNN gene, VNN3. Martin et al. (2001) cloned a full-length VNN3 cDNA encoding a deduced 501-amino acid protein with strong similarity to the mouse vnn3 molecule. Both the mouse and human proteins lack the GPI-anchor motif found in VNN1and VNN2. Northern blot analysis detected a 1.8-kb VNN3 mRNA in human liver, placenta, and peripheral blood leukocytes (PBLs). A 3.8-kb mRNA was observed in PBLs. Martin et al. (2001) found that all vanin proteins are ectoenzymes with pantetheinase activity. They showed that mouse vanin-3 and, by analogy, human VNN3 are secreted molecules.Martin et al. (2001) determined that the human VNN1, VNN2, and VNN3 genes, as well as the mouse vnn1 and vnn3 genes, all contain 7 exons.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD870Hu01 Recombinant Vanin 3 (VNN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD870Hu01 Polyclonal Antibody to Vanin 3 (VNN3) WB; IHC; ICC; IP.
MAD870Hu21 Monoclonal Antibody to Vanin 3 (VNN3) WB; IHC; ICC; IP.
Assay Kits SED870Hu ELISA Kit for Vanin 3 (VNN3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD870Mu01 Recombinant Vanin 3 (VNN3) Positive Control; Immunogen; SDS-PAGE; WB.
RPD870Mu02 Recombinant Vanin 3 (VNN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD870Mu01 Polyclonal Antibody to Vanin 3 (VNN3) WB; IHC; ICC; IP.
PAD870Mu02 Polyclonal Antibody to Vanin 3 (VNN3) WB; IHC; ICC; IP.
Assay Kits SED870Mu ELISA Kit for Vanin 3 (VNN3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vanin 3 (VNN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vanin 3 (VNN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vanin 3 (VNN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vanin 3 (VNN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vanin 3 (VNN3) ELISA Kit Customized Service Offer
  1. "Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes."Immunogenetics 53:296-306(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Alternative spliced variants in the pantetheinase family of genes expressed in human neutrophils."Gene 426:57-64(2008) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "An ESTs description of the new vanin gene family conserved from fly to human."Immunogenetics 49:964-972(1999) [PubMed] [Europe PMC] [Abstract]
  6. "Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines."J. Invest. Dermatol. 129:2167-2174(2009) [PubMed] [Europe PMC] [Abstract]