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Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3)

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ACS3; FACL3; LACS3; Fatty-Acid-Coenzyme A Ligase,Long-Chain 3; Long-chain acyl-CoA synthetase 3

Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3)
CCC D673
HGNC 3570
MGI 1921455
PubMed 21328461
RGD 70552
UniProt O95573
Wiki ACSL3
Long-chain-fatty-acid--CoA ligase 3 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.
This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD673Hu01 Recombinant Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Polyclonal Antibody Customized Service Offer
Assay Kits SED673Hu ELISA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD673Mu01 Recombinant Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD673Mu01 Polyclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) WB; IHC; ICC; IP.
Assay Kits SED673Mu ELISA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 3 (ACSL3) ELISA Kit Customized Service Offer
  1. "Human acyl-coenzyme A synthetase 3 cDNA and localization of its gene (ACS3) to chromosome band 2q34-q35."Genomics 42:180-181(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene."Gene 278:185-192(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Long chain acyl-CoA synthetase 3-mediated phosphatidylcholine synthesis is required for assembly of very low density lipoproteins in human hepatoma Huh7 cells."J. Biol. Chem. 283:849-854(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]