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Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM)

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MCAD; MCADH; ACAD1; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM)
CCC D662
HGNC 89
MGI 87867
PubMed 15832312
RGD 2012
UniProt P11310
Wiki ACADM
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain) is a gene that provides instructions for making an enzyme called acyl-coenzyme A dehydrogenase that is important for breaking down (degrading) a certain group of fats called medium-chain fatty acids. These fatty acids are found in foods such as milk and certain oils, and they are also stored in the body's fat tissue. Medium-chain fatty acids are also produced when larger fatty acids are degraded. The acyl-coenzyme A dehydrogenase for medium-chain fatty acids (ACADM) enzyme is essential for converting these particular fatty acids to energy, especially during periods without food (fasting). The ACADM enzyme functions in mitochondria, the energy-producing centers within cells. It is found in the mitochondria of several types of tissues, particularly the liver.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD662Hu01 Recombinant Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD662Mu01 Recombinant Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD662Mu01 Polyclonal Antibody to Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) ELISA Kit Customized Service Offer
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  6. , Submitted (MAR-2007) to UniProtKB
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  19. "Molecular characterization of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: identification of a lys329 to glu mutation in the MCAD gene, and expression of inactive mutant enzyme protein in E. coli."Hum. Genet. 86:545-551(1991) [PubMed] [Europe PMC] [Abstract]
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  21. "Disease-causing mutations in exon 11 of the medium-chain acyl-CoA dehydrogenase gene."Am. J. Hum. Genet. 54:975-988(1994) [PubMed] [Europe PMC] [Abstract]
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  24. "The molecular basis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in compound heterozygous patients: is there correlation between genotype and phenotype?"Hum. Mol. Genet. 6:695-707(1997) [PubMed] [Europe PMC] [Abstract]
  25. "Biochemical characterization of a variant human medium-chain acyl-CoA dehydrogenase with a disease-associated mutation localized in the active site."Biochem. J. 337:225-230(1999) [PubMed] [Europe PMC] [Abstract]
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  28. "Molecular and functional characterization of mild MCAD deficiency."Hum. Genet. 108:404-408(2001) [PubMed] [Europe PMC] [Abstract]
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