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Apelin also known as APLN is a peptide which is encoded by the APLN gene. Apelin is the endogenous ligand for the G-protein-coupled APJ receptor that is expressed at the surface of some cell types. It is widely expressed in various organs such as the heart, lung, kidney, liver, adipose tissue,gastrointestinal tract, brain, adrenal glands, endothelium, and human plasma.
The gene encodes a 77-amino acid polypeptide that includes a secretory signal sequence. Synthetic 36-amino acid apelin (apelin-36), corresponding to the most C-terminal 36 residues of preproapelin, caused the acidification of cells expressing transfected APJ, but not other receptors. Apelin is an endogenous ligand for the APJ receptor.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD066Hu01 | Recombinant Apelin (APLN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPD066Hu02 | Recombinant Apelin (APLN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| SPD066Hu01 | Synthetic Apelin (APLN) | Immunogen; Blocking Peptide. | |
| CPD066Hu21 | OVA Conjugated Apelin (APLN) | Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAD066Hu01 | Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. |
| LAD066Hu71 | Biotin-Linked Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC. | |
| LAD066Hu81 | FITC-Linked Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IF. | |
| PAD066Hu02 | Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. | |
| PAD066Hu03 | Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. | |
| PAD066Hu08 | Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. | |
| PAD066Hu09 | Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. | |
| Assay Kits | CED066Hu | ELISA Kit for Apelin (APLN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SED066Hu | ELISA Kit for Apelin (APLN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD066Mu01 | Recombinant Apelin (APLN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPD066Mu02 | Recombinant Apelin (APLN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAD066Mu01 | Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. |
| PAD066Mu02 | Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. | |
| Assay Kits | CED066Mu | ELISA Kit for Apelin (APLN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD066Ra01 | Recombinant Apelin (APLN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAD066Ra01 | Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. |
| LAD066Ra71 | Biotin-Linked Polyclonal Antibody to Apelin (APLN) | WB; IHC; ICC. | |
| MAD066Ra21 | Monoclonal Antibody to Apelin (APLN) | WB; IHC; ICC; IP. | |
| Assay Kits | CED066Ra | ELISA Kit for Apelin (APLN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SED066Ra | ELISA Kit for Apelin (APLN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor."Biochem. Biophys. Res. Commun. 251:471-476(1998) [PubMed] [Europe PMC] [Abstract]
- "Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum."Biochim. Biophys. Acta 1452:25-35(1999) [PubMed] [Europe PMC] [Abstract]
- "Characterization of apelin, the ligand for the APJ receptor."J. Neurochem. 74:34-41(2000) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry."J. Virol. 74:11972-11976(2000) [PubMed] [Europe PMC] [Abstract]