Endothelin 3 (EDN3)

Endothelin-3 is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Endothelin 3 (EDN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Endothelin 3 (EDN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endothelin 3 (EDN3) Polyclonal Antibody Customized Service Offer
Assay Kits CEC465Hu ELISA Kit for Endothelin 3 (EDN3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC465Mu01 Recombinant Endothelin 3 (EDN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Endothelin 3 (EDN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endothelin 3 (EDN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Endothelin 3 (EDN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endothelin 3 (EDN3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC465Ra01 Recombinant Endothelin 3 (EDN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC465Ra01 Polyclonal Antibody to Endothelin 3 (EDN3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Endothelin 3 (EDN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endothelin 3 (EDN3) ELISA Kit Customized Service Offer
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  13. "SOX10 mutations in chronic intestinal pseudo-obstruction suggest a complex physiopathological mechanism."Hum. Genet. 111:198-206(2002) [PubMed] [Europe PMC] [Abstract]