Calcium Binding Protein P22 (CHP)

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SLC9A1BP; Calcineurin homologous protein; Calcineurin B-like protein; EF-hand calcium-binding domain-containing protein p22

Calcium Binding Protein P22 (CHP)

Calcium binding protein P22 is a phosphoprotein that binds to the sodium-potassium exchangers (NHEs). This protein serves as an essential cofactor which supports the physiological activity of NHE family members. It has protein sequence similarity to calcineurin B and it is also known to be an endogenous inhibitor of calcineurin activity.

A partial sequence obtained from this screen was used to clone a novel full-length cDNA, designated CHP, from a second B-cell library. The deduced 195-amino acid protein contains 2 distinct and 2 potential EF-hand Ca(2+)-binding motifs and shares 43% and 33% identity with calcineurin B and calmodulin, respectively. It also shares 99% sequence identity with the rat homolog. Northern blot analysis demonstrated expression of a 4-kb CHP transcript in all 8 fetal tissues examined.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calcium Binding Protein P22 (CHP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calcium Binding Protein P22 (CHP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calcium Binding Protein P22 (CHP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calcium Binding Protein P22 (CHP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calcium Binding Protein P22 (CHP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calcium Binding Protein P22 (CHP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calcium Binding Protein P22 (CHP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calcium Binding Protein P22 (CHP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calcium Binding Protein P22 (CHP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calcium Binding Protein P22 (CHP) ELISA Kit Customized Service Offer
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