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Nucleoporin 62 (NUP62)

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IBSN; p62; SNDI; Nuclear Pore Glycoprotein p62; Nucleoporin 62kDa

Nucleoporin 62 (NUP62)
CCC C257
HGNC 8066
MGI 1351500
PubMed 21673506
RGD 619938
UniProt P37198
Wiki NUP62

Nucleoporin p62 (p62) is a protein complex associated with the nuclear envelope. The p62 protein remains associated with the nuclear pore complex-lamina fraction. p62 is synthesized as a soluble cytoplasmic precursor of 61 kDa followed by modification that involve addition of N-acetylglucosamine residues. followed by association with other complex proteins.

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC257Hu01 Recombinant Nucleoporin 62 (NUP62) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC257Hu01 Polyclonal Antibody to Nucleoporin 62 (NUP62) WB; IHC; ICC; IP.
MAC257Hu22 Monoclonal Antibody to Nucleoporin 62 (NUP62) WB; IHC; ICC; IP.
Assay Kits SEC257Hu ELISA Kit for Nucleoporin 62 (NUP62) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleoporin 62 (NUP62) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleoporin 62 (NUP62) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleoporin 62 (NUP62) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleoporin 62 (NUP62) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleoporin 62 (NUP62) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC257Ra01 Recombinant Nucleoporin 62 (NUP62) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Nucleoporin 62 (NUP62) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleoporin 62 (NUP62) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleoporin 62 (NUP62) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleoporin 62 (NUP62) ELISA Kit Customized Service Offer
  1. "Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization."Eur. J. Cell Biol. 55:17-30(1991) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
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  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Hikeshi, a nuclear import carrier for hsp70s, protects cells from heat shock-induced nuclear damage."Cell 149:578-589(2012) [PubMed] [Europe PMC] [Abstract]
  11. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Mutated nup62 causes autosomal recessive infantile bilateral striatal necrosis."Ann. Neurol. 60:214-222(2006) [PubMed] [Europe PMC] [Abstract]