Growth Differentiation Factor 1 (GDF1)

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Embryonic growth/differentiation factor 1

Growth Differentiation Factor 1 (GDF1)

Growth differentiation factor-1 (GDF1) is a protein belonging to the transforming growth factor beta superfamily that has a role in left-right patterning and mesoderm induction during embryonic development. It is found in the brain, spinal cord and peripheral nerves of embryos

This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC108Hu01 Recombinant Growth Differentiation Factor 1 (GDF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC108Hu01 Polyclonal Antibody to Growth Differentiation Factor 1 (GDF1) WB; IHC; ICC; IP.
MAC108Hu22 Monoclonal Antibody to Growth Differentiation Factor 1 (GDF1) WB; IHC; ICC; IP.
Assay Kits SEC108Hu ELISA Kit for Growth Differentiation Factor 1 (GDF1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC108Hu CLIA Kit for Growth Differentiation Factor 1 (GDF1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC108Mu01 Recombinant Growth Differentiation Factor 1 (GDF1) Positive Control; Immunogen; SDS-PAGE; WB.
RPC108Mu02 Recombinant Growth Differentiation Factor 1 (GDF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC108Mu01 Polyclonal Antibody to Growth Differentiation Factor 1 (GDF1) WB,IHC
LAC108Mu71 Biotin-Linked Polyclonal Antibody to Growth Differentiation Factor 1 (GDF1) WB; IHC; ICC.
PAC108Mu02 Polyclonal Antibody to Growth Differentiation Factor 1 (GDF1) WB; IHC; ICC; IP.
Assay Kits SEC108Mu ELISA Kit for Growth Differentiation Factor 1 (GDF1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC108Mu CLIA Kit for Growth Differentiation Factor 1 (GDF1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC108Ra01 Recombinant Growth Differentiation Factor 1 (GDF1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC108Ra01 Polyclonal Antibody to Growth Differentiation Factor 1 (GDF1) WB; IHC; ICC; IP.
MAC108Ra21 Monoclonal Antibody to Growth Differentiation Factor 1 (GDF1) WB; IHC; ICC; IP.
Assay Kits SEC108Ra ELISA Kit for Growth Differentiation Factor 1 (GDF1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC108Ra CLIA Kit for Growth Differentiation Factor 1 (GDF1) Chemiluminescent immunoassay for Antigen Detection.
  1. "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure."Proc. Natl. Acad. Sci. U.S.A. 88:4250-4254(1991) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Recessively inherited right atrial isomerism caused by mutations in growth/differentiation factor 1 (GDF1)."Hum. Mol. Genet. 19:2747-2753(2010) [PubMed] [Europe PMC] [Abstract]
  4. "Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans."Am. J. Hum. Genet. 81:987-994(2007) [PubMed] [Europe PMC] [Abstract]