Major Histocompatibility Complex Class I C (MHCC)

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MHC-C;; HLAC; HLA-JY3; HLC-C; HLA-C; PSORS1 Leukocyte Antigen C; HLA class I histocompatibility antigen, Cw-7 alpha chain

Major Histocompatibility Complex Class I C (MHCC)
HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC086Hu01 Recombinant Major Histocompatibility Complex Class I C (MHCC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC086Hu01 Polyclonal Antibody to Major Histocompatibility Complex Class I C (MHCC) WB,IHC,ICC/IF
MAC086Hu22 Monoclonal Antibody to Major Histocompatibility Complex Class I C (MHCC) WB; IHC; ICC; IP.
MAC086Hu21 Monoclonal Antibody to Major Histocompatibility Complex Class I C (MHCC) WB; IHC; ICC; IP.
Assay Kits SEC086Hu ELISA Kit for Major Histocompatibility Complex Class I C (MHCC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Major Histocompatibility Complex Class I C (MHCC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Major Histocompatibility Complex Class I C (MHCC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Major Histocompatibility Complex Class I C (MHCC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Major Histocompatibility Complex Class I C (MHCC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Major Histocompatibility Complex Class I C (MHCC) ELISA Kit Customized Service Offer
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