Laminin Gamma 1 (LAMC1)

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LAM-C1; LAMB2; S-laminin subunit gamma; Laminin B2 chain

Laminin Gamma 1 (LAMC1)

LAMC1 is the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs seen on Northern analysis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC082Hu01 Recombinant Laminin Gamma 1 (LAMC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC082Hu01 Polyclonal Antibody to Laminin Gamma 1 (LAMC1) WB
MAC082Hu22 Monoclonal Antibody to Laminin Gamma 1 (LAMC1) WB; IHC; ICC; IP.
LAC082Hu71 Biotin-Linked Polyclonal Antibody to Laminin Gamma 1 (LAMC1) WB; IHC; ICC.
Assay Kits SEC082Hu ELISA Kit for Laminin Gamma 1 (LAMC1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC082Mu01 Recombinant Laminin Gamma 1 (LAMC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC082Mu01 Polyclonal Antibody to Laminin Gamma 1 (LAMC1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Laminin Gamma 1 (LAMC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Laminin Gamma 1 (LAMC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC082Ra01 Recombinant Laminin Gamma 1 (LAMC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC082Ra01 Polyclonal Antibody to Laminin Gamma 1 (LAMC1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Laminin Gamma 1 (LAMC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Laminin Gamma 1 (LAMC1) ELISA Kit Customized Service Offer
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