VEGF Co Regulated Chemokine 1 (VCC1)

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CXCL17; SCYB17; DMC; Chemokine C-X-C-Motif Ligand 7; Dendritic cell and monocyte chemokine-like protein

VEGF Co Regulated Chemokine 1 (VCC1)

CXCL17 is a small cytokine belonging to the CXC chemokine family that has been identified in humans and mice. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It is also known as VEGF co-regulated chemokine 1 (VCC-1) and dendritic cell- and monocyte-attracting chemokine-like protein (DMC).

This chemokine is constitutively expressed in the lung.The predicted 119-amino acid protein has a calculated molecular mass of 13.8 kD and shares 71% identity with its mouse homolog. DMC has an N-terminal signal peptide, but no N-glycosylation sites. Secondary structure analysis showed highest similarity to CXCL8 (IL8), whereas circular dichroism analysis revealed that active, purified DMC adopted a secondary structure resembling that of CCL5  and CCL4.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC068Hu01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
APC068Hu01 Active VEGF Co Regulated Chemokine 1 (VCC1) Cell culture; Activity Assays.
Antibodies PAC068Hu01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB
MAC068Hu22 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
LAC068Hu71 Biotin-Linked Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC.
Assay Kits SEC068Hu ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC068Hu CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC068Mu01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
RPC068Mu02 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC068Mu01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAC068Mu02 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
Assay Kits SEC068Mu ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC068Mu CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC068Ra01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC068Ra01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
MAC068Ra21 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
Assay Kits SEC068Ra ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC068Ra CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC068Eq01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC068Eq01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) ELISA Kit Customized Service Offer
  1. "VCC-1, a novel chemokine, promotes tumor growth."Biochem. Biophys. Res. Commun. 350:74-81(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
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  5. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods."J. Immunol. 176:2069-2073(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Broad up-regulation of innate defense factors during acute cholera."Infect. Immun. 75:2343-2350(2007) [PubMed] [Europe PMC] [Abstract]