Glucose Transporter 4 (GLUT4)

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SLC2A4; Solute carrier family 2, facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive

Glucose Transporter 4 (GLUT4)

GLUT4 is the insulin-regulated glucose transporter found in adipose tissues and striated muscle (skeletal and cardiac) that is responsible for insulin-regulated glucose disposal.In the absence of insulin, GLUT4 is sequestered in the interior of muscle and fat cells within lipid bilayers of vesicles. Insulin induces the translocation of GLUT4 from intracellular storage sites to the plasma membrane. Insulin binds to the insulin receptor in its dimeric form.

The receptor phosphorylates and subsequently activates IRS-1, which converts PIP2 to PIP3. PIP3 is bound to PKB (protein kinase B), signaling for PDK1 to phosphorylate PKB. Once phosphorylated, PKB is in its active form and phosphorylates other targets that stimulate GLUT4 to be expressed on the plasma membrane.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC023Hu01 Recombinant Glucose Transporter 4 (GLUT4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC023Hu01 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB; IHC; ICC; IP.
MAC023Hu22 Monoclonal Antibody to Glucose Transporter 4 (GLUT4) WB; IHC; ICC; IP.
Assay Kits SEC023Hu ELISA Kit for Glucose Transporter 4 (GLUT4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC023Mu01 Recombinant Glucose Transporter 4 (GLUT4) Positive Control; Immunogen; SDS-PAGE; WB.
RPC023Mu02 Recombinant Glucose Transporter 4 (GLUT4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC023Mu01 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB; IHC; ICC; IP.
PAC023Mu02 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB; IHC; ICC; IP.
Assay Kits SEC023Mu ELISA Kit for Glucose Transporter 4 (GLUT4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC023Ra01 Recombinant Glucose Transporter 4 (GLUT4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC023Ra01 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB; IHC; ICC; IP.
MAC023Ra21 Monoclonal Antibody to Glucose Transporter 4 (GLUT4) WB; IHC; ICC; IP.
Assay Kits SEC023Ra ELISA Kit for Glucose Transporter 4 (GLUT4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC023Ca01 Recombinant Glucose Transporter 4 (GLUT4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC023Ca01 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB; IHC; ICC; IP.
MAC023Ca21 Monoclonal Antibody to Glucose Transporter 4 (GLUT4) WB; IHC; ICC; IP.
Assay Kits SEC023Ca ELISA Kit for Glucose Transporter 4 (GLUT4) Enzyme-linked immunosorbent assay for Antigen Detection.
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