Superoxide Dismutase 1 (SOD1)

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ALS; ALS1; IPOA; Superoxide Dismutase 1, Soluble; Amyotrophic Lateral Sclerosis 1,Adult; Superoxide dismutase [Cu-Zn]

Superoxide Dismutase 1 (SOD1)

Superoxide dismutase 1, soluble is a human protein and gene. This gene encodes one of three forms of the human superoxide dismutase. SOD1 binds copper and zinc ions and is one of three isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide. Mutations (over 100 identified to date) in this gene have been linked to familial amyotrophic lateral sclerosis. The most frequent mutation are A4V (in the U.S.A.) and H46R (Japan). The most studied ALS mouse model is G93A. Rare transcript variants have been reported for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Hu01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
APB960Hu01 Active Superoxide Dismutase 1 (SOD1) Cell culture; Activity Assays.
Antibodies PAB960Hu01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
MAB960Hu22 Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
LAB960Hu71 Biotin-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC.
Assay Kits SEB960Hu ELISA Kit for Superoxide Dismutase 1 (SOD1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Mu01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB960Mu02 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
APB960Mu01 Active Superoxide Dismutase 1 (SOD1) Cell culture; Activity Assays.
Antibodies PAB960Mu01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
LAB960Mu71 Biotin-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC.
LAB960Mu81 FITC-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IF.
PAB960Mu02 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
Assay Kits SEB960Mu ELISA Kit for Superoxide Dismutase 1 (SOD1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Ra01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
APB960Ra01 Active Superoxide Dismutase 1 (SOD1) Cell culture; Activity Assays.
Antibodies PAB960Ra01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
LAB960Ra71 Biotin-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC.
LAB960Ra81 FITC-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IF.
MAB960Ra21 Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC.
MAB960Ra22 Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
MAB960Ra23 Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
MAB960Ra24 Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
MAB960Ra25 Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
Assay Kits SEB960Ra ELISA Kit for Superoxide Dismutase 1 (SOD1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Superoxide Dismutase 1 (SOD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Superoxide Dismutase 1 (SOD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Superoxide Dismutase 1 (SOD1) ELISA Kit Customized Service Offer

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Rb01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
APB960Rb01 Active Superoxide Dismutase 1 (SOD1) Cell culture; Activity Assays.
Antibodies PAB960Rb51 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB,IHC
LAB960Rb71 Biotin-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC.
LAB960Rb81 FITC-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IF.
PAB960Rb01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
Assay Kits SEB960Rb ELISA Kit for Superoxide Dismutase 1 (SOD1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Po01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
APB960Po01 Active Superoxide Dismutase 1 (SOD1) Cell culture; Activity Assays.
Antibodies PAB960Po01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
Assay Kits SEB960Po ELISA Kit for Superoxide Dismutase 1 (SOD1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Bo01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
APB960Bo01 Active Superoxide Dismutase 1 (SOD1) Cell culture; Activity Assays.
Antibodies PAB960Bo01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
LAB960Bo71 Biotin-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC.
LAB960Bo81 FITC-Linked Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IF.
MAB960Bo22 Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
MAB960Bo21 Monoclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
Assay Kits SEB960Bo ELISA Kit for Superoxide Dismutase 1 (SOD1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Ov01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
APB960Ov01 Active Superoxide Dismutase 1 (SOD1) Cell culture; Activity Assays.
Antibodies PAB960Ov01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Superoxide Dismutase 1 (SOD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Superoxide Dismutase 1 (SOD1) ELISA Kit Customized Service Offer

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Eq01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
APB960Eq01 Active Superoxide Dismutase 1 (SOD1) Cell culture; Activity Assays.
Antibodies PAB960Eq01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Superoxide Dismutase 1 (SOD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Superoxide Dismutase 1 (SOD1) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB960Ga01 Recombinant Superoxide Dismutase 1 (SOD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB960Ga01 Polyclonal Antibody to Superoxide Dismutase 1 (SOD1) WB; IHC; ICC; IP.
Assay Kits SEB960Ga ELISA Kit for Superoxide Dismutase 1 (SOD1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Nucleotide sequence and expression of human chromosome 21-encoded superoxide dismutase mRNA."Proc. Natl. Acad. Sci. U.S.A. 80:5465-5469(1983) [PubMed] [Europe PMC] [Abstract]
  2. "Architecture and anatomy of the chromosomal locus in human chromosome 21 encoding the Cu/Zn superoxide dismutase."EMBO J. 4:77-84(1985) [PubMed] [Europe PMC] [Abstract]
  3. "Human Cu/Zn superoxide dismutase cDNA: isolation of clones synthesising high levels of active or inactive enzyme from an expression library."Nucleic Acids Res. 13:2017-2034(1985) [PubMed] [Europe PMC] [Abstract]
  4. "Comparison of properties between human recombinant and placental copper-zinc SOD."J. Biochem. 104:851-854(1988) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence of human chromosome 21." Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Some sulfhydryl properties and primary structure of human erythrocyte superoxide dismutase."Biochemistry 19:2310-2316(1980) [PubMed] [Europe PMC] [Abstract]
  9. "The complete amino acid sequence of human Cu/Zn superoxide dismutase."FEBS Lett. 120:53-56(1980) [PubMed] [Europe PMC] [Abstract]