Interleukin 7 Receptor (IL7R)

Interleukin-7 receptor is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). 

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB905Hu01 Recombinant Interleukin 7 Receptor (IL7R) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB905Hu01 Polyclonal Antibody to Interleukin 7 Receptor (IL7R) WB; ICC; IHC-P; IHC-F; ELISA.
MAB905Hu22 Monoclonal Antibody to Interleukin 7 Receptor (IL7R) WB; IHC; ICC; IP.
Assay Kits SEB905Hu ELISA Kit for Interleukin 7 Receptor (IL7R) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB905Mu01 Recombinant Interleukin 7 Receptor (IL7R) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB905Mu01 Polyclonal Antibody to Interleukin 7 Receptor (IL7R) WB; IHC; ICC; IP.
LAB905Mu71 Biotin-Linked Polyclonal Antibody to Interleukin 7 Receptor (IL7R) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Interleukin 7 Receptor (IL7R) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 7 Receptor (IL7R) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB905Ra01 Recombinant Interleukin 7 Receptor (IL7R) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB905Ra01 Polyclonal Antibody to Interleukin 7 Receptor (IL7R) WB; IHC; ICC; IP.
MAB905Ra21 Monoclonal Antibody to Interleukin 7 Receptor (IL7R) WB; IHC; ICC; IP.
Assay Kits SEB905Ra ELISA Kit for Interleukin 7 Receptor (IL7R) Enzyme-linked immunosorbent assay for Antigen Detection.
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  9. "Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis."Nat. Genet. 39:1083-1091(2007) [PubMed] [Europe PMC] [Abstract]