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High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1)

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IPO38; HMG14; Non-histone chromosomal protein HMG-14

High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1)
CCC B876
HGNC 4984
MGI 96120
PubMed 16279949
RGD 1307761
UniProt P05114
Wiki HMGN1

Chromosomal protein HMG14 and its close analog HMG17 bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation.

IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin's disease and non-Hodgkin's lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.IPO-38 is identified as a novel serum biomarker of gastric cancer.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB876Hu01 Recombinant High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB876Hu01 Polyclonal Antibody to High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) WB; ICC; IHC-P; IHC-F; ELISA.
MAB876Hu22 Monoclonal Antibody to High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) WB; IHC; ICC; IP.
Assay Kits SEB876Hu ELISA Kit for High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB876Mu01 Recombinant High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB876Mu02 Recombinant High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB876Mu01 Polyclonal Antibody to High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) ELISA Kit Customized Service Offer
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  14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  15. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]