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Coagulation Factor XI (F11)

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FXI; PTA; Fletcher Factor; Prekallikrein; Plasma Thromboplastin Antecedent

Coagulation Factor XI (F11)
CCC B834
HGNC 3529
MGI 99481
PubMed 10961575
RGD 1309364
UniProt P03951
Wiki Factor_XI
Factor XI is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease.Factor XI (FXI) is produced by the liver and circulates as a homo-dimer in its inactive form. The plasma half-life of FXI is approximately 52 hours.
The zymogen factor is activated into factor XIa by factor XIIa (FXIIa), thrombin, and it is also autocatalytic, and FXI is a member of the "contact pathway" due to activation by FXIIa (with includes HMWK, prekallikrein, factor XII, factor XI and factor IX).Factor XIa activates factor IX by selectively cleaving arg-ala and arg-val peptide bonds. Factor IXa, in turn, activates factor X.Inhibitors of factor XIa include protein Z-dependent protease inhibitor (ZPI), which is independent of protein Z.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB834Hu01 Recombinant Coagulation Factor XI (F11) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB834Hu01 Polyclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
MAB834Hu22 Monoclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
MAB834Hu21 Monoclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
MAB834Hu25 Monoclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
MAB834Hu24 Monoclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
MAB834Hu23 Monoclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
MAB834Hu27 Monoclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
Assay Kits SEB834Hu ELISA Kit for Coagulation Factor XI (F11) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB834Mu01 Recombinant Coagulation Factor XI (F11) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB834Mu01 Polyclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
Assay Kits SEB834Mu ELISA Kit for Coagulation Factor XI (F11) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB834Ra01 Recombinant Coagulation Factor XI (F11) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB834Ra01 Polyclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
MAB834Ra21 Monoclonal Antibody to Coagulation Factor XI (F11) WB; IHC; ICC; IP.
Assay Kits SEB834Ra ELISA Kit for Coagulation Factor XI (F11) Enzyme-linked immunosorbent assay for Antigen Detection.
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