Myostatin (MSTN)

Myostatin  is a growth factor that limits muscle tissue growth, i.e. higher concentrations of myostatin in the body may cause the individual to have less developed muscles. The myostatin protein is produced primarily in skeletal muscle cells, circulates in the blood and acts on muscle tissue, apparently by slowing down the development of muscle stem cells. The precise mechanism remains unknown. Its functions in non-mammalian vertebrates appear to be somewhat conserved as muscle-specific actions have been demonstrated in birds. However, it is produced in many different fish tissues, suggesting that it may regulate more than just muscle mass in these vertebrates. Human Myostatin consists of two identical subunits, each consisting of 110 amino acid residues. Its total molecular weight is 25.0 kDa.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB653Hu01 Recombinant Myostatin (MSTN) Positive Control; Immunogen; SDS-PAGE; WB.
EPB653Hu61 Eukaryotic Myostatin (MSTN) Positive Control; Immunogen; SDS-PAGE; WB.
CPB653Hu21 OVA Conjugated Myostatin (MSTN) Immunogen; SDS-PAGE; WB.
APB653Hu61 Active Myostatin (MSTN) Cell culture; Activity Assays.
APB653Hu01 Active Myostatin (MSTN) Cell culture; Activity Assays.
Antibodies PAB653Hu01 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
MAB653Hu22 Monoclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
LAB653Hu71 Biotin-Linked Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC.
MAB653Hu21 Monoclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
PAB653Hu06 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
PAB653Hu08 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
Assay Kits SCB653Hu CLIA Kit for Myostatin (MSTN) Chemiluminescent immunoassay for Antigen Detection.
CEB653Hu ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB653Hu ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB653Mu01 Recombinant Myostatin (MSTN) Positive Control; Immunogen; SDS-PAGE; WB.
RPB653Mu02 Recombinant Myostatin (MSTN) Positive Control; Immunogen; SDS-PAGE; WB.
CPB653Mu21 OVA Conjugated Myostatin (MSTN) Immunogen; SDS-PAGE; WB.
APB653Mu01 Active Myostatin (MSTN) Cell culture; Activity Assays.
Antibodies PAB653Mu01 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
LAB653Mu71 Biotin-Linked Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC.
PAB653Mu02 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
PAB653Mu08 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
Assay Kits CEB653Mu ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB653Mu ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB653Ra01 Recombinant Myostatin (MSTN) Positive Control; Immunogen; SDS-PAGE; WB.
CPB653Ra21 OVA Conjugated Myostatin (MSTN) Immunogen; SDS-PAGE; WB.
APB653Ra01 Active Myostatin (MSTN) Cell culture; Activity Assays.
Antibodies PAB653Ra01 Polyclonal Antibody to Myostatin (MSTN) WB,IHC
LAB653Ra71 Biotin-Linked Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC.
MAB653Ra21 Monoclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
PAB653Ra08 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
Assay Kits SCB653Ra CLIA Kit for Myostatin (MSTN) Chemiluminescent immunoassay for Antigen Detection.
CEB653Ra ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB653Ra ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB653Po01 Recombinant Myostatin (MSTN) Positive Control; Immunogen; SDS-PAGE; WB.
CPB653Po21 OVA Conjugated Myostatin (MSTN) Immunogen; SDS-PAGE; WB.
Antibodies PAB653Po01 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
MAB653Po21 Monoclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
Assay Kits SEB653Po ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB653Bo01 Recombinant Myostatin (MSTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB653Bo01 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
LAB653Bo71 Biotin-Linked Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC.
LAB653Bo81 FITC-Linked Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IF.
MAB653Bo21 Monoclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Myostatin (MSTN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myostatin (MSTN) ELISA Kit Customized Service Offer

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myostatin (MSTN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myostatin (MSTN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myostatin (MSTN) Polyclonal Antibody Customized Service Offer
Assay Kits SEB653Ov ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB653Ga01 Recombinant Myostatin (MSTN) Positive Control; Immunogen; SDS-PAGE; WB.
CPB653Ga21 OVA Conjugated Myostatin (MSTN) Immunogen; SDS-PAGE; WB.
Antibodies PAB653Ga01 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
MAB653Ga21 Monoclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
PAB653Ga08 Polyclonal Antibody to Myostatin (MSTN) WB; IHC; ICC; IP.
Assay Kits SEB653Ga ELISA Kit for Myostatin (MSTN) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB653Ga CLIA Kit for Myostatin (MSTN) Chemiluminescent immunoassay for Antigen Detection.
  1. "Double muscling in cattle due to mutations in the myostatin gene."Proc. Natl. Acad. Sci. U.S.A. 94:12457-12461(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting."Proc. Natl. Acad. Sci. U.S.A. 95:14938-14943(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Human adaptive evolution at myostatin (GDF8), a regulator of muscle growth."Am. J. Hum. Genet. 79:1089-1097(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains."Mol. Endocrinol. 17:1144-1154(2003) [PubMed] [Europe PMC] [Abstract]
  6. "Myostatin mutation associated with gross muscle hypertrophy in a child."N. Engl. J. Med. 350:2682-2688(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development."J. Med. Invest. 54:276-288(2007) [PubMed] [Europe PMC] [Abstract]