Tetraspanin 25 (TSPAN25)

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CD53; MOX44; TSPAN25; Leukocyte surface antigen CD53; Cell surface glycoprotein CD53

Tetraspanin 25 (TSPAN25)

CD53 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.

This protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetraspanin 25 (TSPAN25) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetraspanin 25 (TSPAN25) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetraspanin 25 (TSPAN25) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tetraspanin 25 (TSPAN25) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tetraspanin 25 (TSPAN25) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetraspanin 25 (TSPAN25) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetraspanin 25 (TSPAN25) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetraspanin 25 (TSPAN25) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tetraspanin 25 (TSPAN25) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tetraspanin 25 (TSPAN25) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetraspanin 25 (TSPAN25) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetraspanin 25 (TSPAN25) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetraspanin 25 (TSPAN25) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tetraspanin 25 (TSPAN25) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tetraspanin 25 (TSPAN25) ELISA Kit Customized Service Offer
  1. "The human leucocyte surface antigen CD53 is a protein structurally similar to the CD37 and MRC OX-44 antigens."Immunogenetics 32:281-285(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Identification and analysis of cDNA clones encoding CD53. A pan-leukocyte antigen related to membrane transport proteins."J. Immunol. 145:4322-4325(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "SCIMP, a transmembrane adapter protein involved in major histocompatibility complex class II signaling."Mol. Cell. Biol. 31:4550-4562(2011) [PubMed] [Europe PMC] [Abstract]