Ezrin (EZR)

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CVL; Ezrin; VIL2; CVIL; CVL; Villin 2; p81; Cytovillin

Ezrin (EZR)

Cytovillin is a microvillar cytoplasmic peripheral membrane protein, with prominent expression in vivo in placental syncytiotrophoblasts and certain human tumors. Cytovillin cDNA was cloned from a human placental lambda gt11 library using affinity purified antibodies.

The identity of cytovillin cDNA clones was confirmed by expression of cytovillin in Escherichia coli and using antibodies raised against the expressed fusion protein in comparison with antibodies against cytovillin purified from cultured human choriocarcinoma cells. In these cells Northern blotting analysis identified a major 3.5-kilobase cytovillin mRNA. The cDNA encodes a protein of 575 amino acids corresponding to a molecular weight of 68,084.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB297Hu01 Recombinant Ezrin (EZR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB297Hu01 Polyclonal Antibody to Ezrin (EZR) WB; IHC; ICC; IP.
MAB297Hu21 Monoclonal Antibody to Ezrin (EZR) WB; IHC; ICC; IP.
Assay Kits SEB297Hu ELISA Kit for Ezrin (EZR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ezrin (EZR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ezrin (EZR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ezrin (EZR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ezrin (EZR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ezrin (EZR) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ezrin (EZR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ezrin (EZR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ezrin (EZR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ezrin (EZR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ezrin (EZR) ELISA Kit Customized Service Offer
  1. "cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1."EMBO J. 8:4133-4142(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Cytovillin, a microvillar Mr 75,000 protein. cDNA sequence, prokaryotic expression, and chromosomal localization."J. Biol. Chem. 264:16727-16732(1989) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes."Biochem. Biophys. Res. Commun. 224:666-674(1996) [PubMed] [Europe PMC] [Abstract]