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Integrin Alpha 2 (ITGa2)

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CD49b; BR; GPIa; VLA-2; VLAA2; Platelet membrane glycoprotein Ia; Alpha 2 Subunit Of VLA-2 Receptor; Very Late Activation Proteins 2 Receptor; Collagen receptor; VLA-2 alpha

Integrin Alpha 2 (ITGa2)
CCC B228
HGNC 6137
MGI 96600
PubMed 20959644
RGD 621632
UniProt P17301
Wiki CD49b

The CD49b protein is an integrin alpha subunit. It makes up half of the α2β1 integrin duplex. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.Kunicki et al. (1997) identified 2 silent, linked polymorphisms, 807C-T and 873G-A, within the coding region of the ITGA2 gene that are associated with GP Ia/IIa surface expression, i.e., the number of GP Ia/IIa copies on the platelet membrane. High surface expression was found in platelets derived from 807T homozygotes, whereas low surface expression was found in platelets from 807C homozygotes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB228Hu01 Recombinant Integrin Alpha 2 (ITGa2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB228Hu02 Recombinant Integrin Alpha 2 (ITGa2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB228Hu03 Recombinant Integrin Alpha 2 (ITGa2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB228Hu01 Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IP.
MAB228Hu22 Monoclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IP.
PAB228Hu02 Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IP.
PAB228Hu03 Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IP.
LAB228Hu71 Biotin-Linked Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC.
LAB228Hu81 FITC-Linked Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IF.
Assay Kits SEB228Hu ELISA Kit for Integrin Alpha 2 (ITGa2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB228Mu01 Recombinant Integrin Alpha 2 (ITGa2) Positive Control; Immunogen; SDS-PAGE; WB.
APB228Mu01 Active Integrin Alpha 2 (ITGa2) Cell culture; Activity Assays.
Antibodies PAB228Mu01 Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Integrin Alpha 2 (ITGa2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Integrin Alpha 2 (ITGa2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB228Ra01 Recombinant Integrin Alpha 2 (ITGa2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB228Ra01 Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IP.
MAB228Ra21 Monoclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IP.
Assay Kits SEB228Ra ELISA Kit for Integrin Alpha 2 (ITGa2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB228Bo01 Recombinant Integrin Alpha 2 (ITGa2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB228Bo01 Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IP.
LAB228Bo81 FITC-Linked Polyclonal Antibody to Integrin Alpha 2 (ITGa2) WB; IHC; ICC; IF.
Assay Kits n/a CLIA Kit for Integrin Alpha 2 (ITGa2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Integrin Alpha 2 (ITGa2) ELISA Kit Customized Service Offer
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