Gastrin (GT)

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GAST; GAS; Gastrin component I; Big gastrin; Gastrin component II; Gastrin component III

Gastrin (GT)

Gastrin is a major physiological regulator of gastric acid secretion. It also has an important trophic or growth-promoting influence on the gastric mucosa. Gastrin is synthesized in G cells, which are located in gastric pits, primarily in the antrum region of the stomach and binds receptors found predominantly on parietal and enterochromaffin-like cells.In humans, gastrin is a hormone that stimulates secretion of gastric acid by the parietal cells of the stomach.

It is released by G cells in the stomach and duodenum.Gastrin is a linear peptide hormone produced by G cells of the duodenum and in the pyloric antrum of the stomach. In the Zollinger-Ellison syndrome, gastrin is produced at excessive levels, often by a gastrinoma of the antrum or the pancreas.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB224Hu01 Recombinant Gastrin (GT) Positive Control; Immunogen; SDS-PAGE; WB.
SPB224Hu01 Synthetic Gastrin (GT) Immunogen; Blocking Peptide.
SPB224Hu02 Synthetic Gastrin (GT) Immunogen; Blocking Peptide.
CPB224Hu21 OVA Conjugated Gastrin (GT) Immunogen; SDS-PAGE; WB.
CPB224Hu22 OVA Conjugated Gastrin (GT) Immunogen; SDS-PAGE; WB.
Antibodies PAB224Hu01 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
MAB224Hu22 Monoclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
LAB224Hu71 Biotin-Linked Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC.
LAB224Hu81 FITC-Linked Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IF.
PAB224Hu02 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
PAB224Hu03 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
MAB224Hu21 Monoclonal Antibody to Gastrin (GT) WB.
Assay Kits CEB224Hu ELISA Kit for Gastrin (GT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB224Mu01 Recombinant Gastrin (GT) Positive Control; Immunogen; SDS-PAGE; WB.
RPB224Mu02 Recombinant Gastrin (GT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB224Mu01 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
LAB224Mu81 FITC-Linked Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IF.
LAB224Mu71 Biotin-Linked Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC.
PAB224Mu02 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
Assay Kits CEB224Mu ELISA Kit for Gastrin (GT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB224Ra01 Recombinant Gastrin (GT) Positive Control; Immunogen; SDS-PAGE; WB.
RPB224Ra02 Recombinant Gastrin (GT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB224Ra01 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
LAB224Ra81 FITC-Linked Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IF.
LAB224Ra71 Biotin-Linked Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC.
MAB224Ra21 Monoclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
PAB224Ra02 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
Assay Kits CEB224Ra ELISA Kit for Gastrin (GT) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB224Ra ELISA Kit for Gastrin (GT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB224Gu01 Recombinant Gastrin (GT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB224Gu01 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
MAB224Gu21 Monoclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
Assay Kits CEB224Gu ELISA Kit for Gastrin (GT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB224Ca01 Recombinant Gastrin (GT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB224Ca01 Polyclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
MAB224Ca21 Monoclonal Antibody to Gastrin (GT) WB; IHC; ICC; IP.
Assay Kits CEB224Ca ELISA Kit for Gastrin (GT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Gastrin (GT) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Gastrin (GT) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Gastrin (GT) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Gastrin (GT) CLIA Kit Customized Service Offer
n/a ELISA Kit for Gastrin (GT) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Gastrin (GT) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Gastrin (GT) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Gastrin (GT) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Gastrin (GT) CLIA Kit Customized Service Offer
n/a ELISA Kit for Gastrin (GT) ELISA Kit Customized Service Offer
  1. "Expression of human gastrin gene in normal and gastrinoma tissues."Gene 50:345-352(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Structural analysis of the gene encoding human gastrin: the large intron contains an Alu sequence."Proc. Natl. Acad. Sci. U.S.A. 81:4662-4666(1984) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular cloning of the human gastrin gene."Nucleic Acids Res. 11:8197-8203(1983) [PubMed] [Europe PMC] [Abstract]
  4. "Molecular cloning of human gastrin cDNA: evidence for evolution of gastrin by gene duplication."Proc. Natl. Acad. Sci. U.S.A. 80:2866-2869(1983) [PubMed] [Europe PMC] [Abstract]
  5. "Structure of a human gastrin gene."Proc. Natl. Acad. Sci. U.S.A. 81:1067-1069(1984) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular cloning of human gastrin precursor cDNA."Gene 26:53-57(1983) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Identification of gastrin component I as gastrin-71. The largest possible bioactive progastrin product."Eur. J. Biochem. 223:765-773(1994) [PubMed] [Europe PMC] [Abstract]
  9. "Structures of human gastrins I and II."Nature 209:583-585(1966) [PubMed] [Europe PMC] [Abstract]
  10. "Purification and structural determination of urinary NH2-terminal big gastrin fragments."Biochem. Biophys. Res. Commun. 160:1364-1370(1989) [PubMed] [Europe PMC] [Abstract]
  11. "Aminoacid constitution of two gastrins isolated from Zollinger-Ellison tumour tissue."Gut 10:603-608(1969) [PubMed] [Europe PMC] [Abstract]
  12. "The human gastrin precursor. Characterization of phosphorylated forms and fragments."Biochem. J. 256:951-957(1988) [PubMed] [Europe PMC] [Abstract]
  13. "Post-poly(Glu) cleavage and degradation modified by O-sulfated tyrosine: a novel post-translational processing mechanism."EMBO J. 14:389-396(1995) [PubMed] [Europe PMC] [Abstract]
  14. "Tyrosine O-sulfation promotes proteolytic processing of progastrin."EMBO J. 14:3073-3079(1995) [PubMed] [Europe PMC] [Abstract]
  15. "Metabolism and acid secretory effect of sulfated and nonsulfated gastrin-6 in humans."Am. J. Physiol. 279:G903-G909(2000) [PubMed] [Europe PMC] [Abstract]