Myogenin (MYOG)

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MYF4; bHLHc3; Myogenic Factor 4; Class C basic helix-loop-helix protein 3

Myogenin (MYOG)

Myogenin is a muscle-specific basic-helix-loop-helix (bHLH) transcription factor involved in the coordination of skeletal muscle development and repair. Myogenin is a member of the MyoD family of transcription factors, which also includes MyoD, Myf5, and Mrf4.
In mice, myogenin is essential for the development of functional skeletal muscle. When the DNA coding for myogenin was knocked out of the mouse genome, severe skeletal muscle defects were observed. Mice lacking both copies of myogenin (homozygous-null) suffer from perinatal lethality due to the lack of mature secondary skeletal muscle fibers throughout the body. In cell culture, myogenin can induce myogenesis in a variety of non-muscle cell types.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB109Hu01 Recombinant Myogenin (MYOG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB109Hu01 Polyclonal Antibody to Myogenin (MYOG) WB; IHC; ICC; IP.
MAB109Hu22 Monoclonal Antibody to Myogenin (MYOG) WB; IHC; ICC; IP.
Assay Kits SEB109Hu ELISA Kit for Myogenin (MYOG) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB109Mu01 Recombinant Myogenin (MYOG) Positive Control; Immunogen; SDS-PAGE; WB.
RPB109Mu02 Recombinant Myogenin (MYOG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB109Mu01 Polyclonal Antibody to Myogenin (MYOG) WB; IHC; ICC; IP.
PAB109Mu02 Polyclonal Antibody to Myogenin (MYOG) WB; IHC; ICC; IP.
Assay Kits SEB109Mu ELISA Kit for Myogenin (MYOG) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB109Ra01 Recombinant Myogenin (MYOG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB109Ra01 Polyclonal Antibody to Myogenin (MYOG) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Myogenin (MYOG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myogenin (MYOG) ELISA Kit Customized Service Offer
  1. "Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products."EMBO J. 8:3617-3625(1989) [PubMed] [Europe PMC] [Abstract]
  2. ErratumEMBO J. 9:592-592(1990)
  3. "Transcription of the muscle regulatory gene Myf4 is regulated by serum components, peptide growth factors and signaling pathways involving G proteins."J. Cell Biol. 115:905-917(1991) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]