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Mucin 20 (MUC20)

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Mucin 20 (MUC20)
CCC A995
HGNC 23282
MGI 2385039
PubMed 12478110
RGD 1304865
UniProt Q8N307
Wiki MUC20

Mucin 20, cell surface associated is a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA995Hu01 Recombinant Mucin 20 (MUC20) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA995Hu01 Polyclonal Antibody to Mucin 20 (MUC20) WB; IHC; ICC; IP.
MAA995Hu22 Monoclonal Antibody to Mucin 20 (MUC20) WB; IHC; ICC; IP.
Assay Kits SEA995Hu ELISA Kit for Mucin 20 (MUC20) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA995Mu01 Recombinant Mucin 20 (MUC20) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA995Mu01 Polyclonal Antibody to Mucin 20 (MUC20) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Mucin 20 (MUC20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mucin 20 (MUC20) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA995Ra01 Recombinant Mucin 20 (MUC20) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA995Ra01 Polyclonal Antibody to Mucin 20 (MUC20) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Mucin 20 (MUC20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mucin 20 (MUC20) ELISA Kit Customized Service Offer
  1. "Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney."J. Biol. Chem. 279:1968-1979(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
  7. "MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met."Mol. Cell. Biol. 24:7456-7468(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Tandem repeats polymorphism of MUC20 is an independent factor for the progression of immunoglobulin A nephropathy."Am. J. Nephrol. 26:43-49(2006) [PubMed] [Europe PMC] [Abstract]
  9. "Mucin gene expression in human male urogenital tract epithelia."Hum. Reprod. 21:2783-2793(2006) [PubMed] [Europe PMC] [Abstract]